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Details

Stereochemistry ABSOLUTE
Molecular Formula C19H25NO2
Molecular Weight 299.4073
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PROXORPHAN

SMILES

[H][C@@]12CCOC[C@@]13CCN(CC4CC4)[C@@H]2CC5=C3C=C(O)C=C5

InChI

InChIKey=USEITRSTDJBLBU-UHOSZYNNSA-N
InChI=1S/C19H25NO2/c21-15-4-3-14-9-18-16-5-8-22-12-19(16,17(14)10-15)6-7-20(18)11-13-1-2-13/h3-4,10,13,16,18,21H,1-2,5-9,11-12H2/t16-,18+,19-/m0/s1

HIDE SMILES / InChI

Molecular Formula C19H25NO2
Molecular Weight 299.4073
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 3 / 3
E/Z Centers 0
Optical Activity UNSPECIFIED

Proxorphan is a N-substituted 6-oxamorphinane patented by American pharmaceutical company Bristol-Myers Co. as opioid analgesic and antitussive drug. Proxorphan acts as a κ-opioid receptor partial agonist and to a lesser extent as a μ-opioid receptor partial agonist.

Approval Year

PubMed

PubMed

TitleDatePubMed
Patents

Patents

Substance Class Chemical
Created
by admin
on Thu Jul 06 01:49:02 UTC 2023
Edited
by admin
on Thu Jul 06 01:49:02 UTC 2023
Record UNII
TFE8T279QV
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PROXORPHAN
INN  
INN  
Official Name English
6-OXAMORPHINAN-3-OL, 17-(CYCLOPROPYLMETHYL)-
Systematic Name English
proxorphan [INN]
Common Name English
(-)-(4AR,5R,10BS)-13-(CYCLOPROPYLMETHYL)-4,4A,5,6-TETRAHYDRO-3H-5,10B-(IMINOETHANO)-1H-NAPHTHO(1,2-C)-PYRAN-9-OL
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C1506
Created by admin on Thu Jul 06 01:49:02 UTC 2023 , Edited by admin on Thu Jul 06 01:49:02 UTC 2023
NCI_THESAURUS C67413
Created by admin on Thu Jul 06 01:49:02 UTC 2023 , Edited by admin on Thu Jul 06 01:49:02 UTC 2023
Code System Code Type Description
CAS
69815-38-9
Created by admin on Thu Jul 06 01:49:02 UTC 2023 , Edited by admin on Thu Jul 06 01:49:02 UTC 2023
PRIMARY
PUBCHEM
5361874
Created by admin on Thu Jul 06 01:49:02 UTC 2023 , Edited by admin on Thu Jul 06 01:49:02 UTC 2023
PRIMARY
EVMPD
SUB10151MIG
Created by admin on Thu Jul 06 01:49:02 UTC 2023 , Edited by admin on Thu Jul 06 01:49:02 UTC 2023
PRIMARY
FDA UNII
TFE8T279QV
Created by admin on Thu Jul 06 01:49:02 UTC 2023 , Edited by admin on Thu Jul 06 01:49:02 UTC 2023
PRIMARY
INN
4813
Created by admin on Thu Jul 06 01:49:02 UTC 2023 , Edited by admin on Thu Jul 06 01:49:02 UTC 2023
PRIMARY
NCI_THESAURUS
C97088
Created by admin on Thu Jul 06 01:49:02 UTC 2023 , Edited by admin on Thu Jul 06 01:49:02 UTC 2023
PRIMARY
ChEMBL
CHEMBL2110701
Created by admin on Thu Jul 06 01:49:02 UTC 2023 , Edited by admin on Thu Jul 06 01:49:02 UTC 2023
PRIMARY
SMS_ID
100000080860
Created by admin on Thu Jul 06 01:49:02 UTC 2023 , Edited by admin on Thu Jul 06 01:49:02 UTC 2023
PRIMARY
EPA CompTox
DTXSID90990082
Created by admin on Thu Jul 06 01:49:02 UTC 2023 , Edited by admin on Thu Jul 06 01:49:02 UTC 2023
PRIMARY
WIKIPEDIA
Proxorphan
Created by admin on Thu Jul 06 01:49:02 UTC 2023 , Edited by admin on Thu Jul 06 01:49:02 UTC 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
Related Record Type Details
ACTIVE MOIETY