U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
139594
Substance Class Protein
Created
by admin
on Sat Dec 16 14:53:04 GMT 2023
Edited
by admin
on Sat Dec 16 14:53:04 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
TF5MPQ8WGY
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Zolbetuximab
USAN   INN  
Official Name English
Zolbetuximab [WHO-DD]
Common Name English
ZOLBETUXIMAB [USAN]
Common Name English
CLAUDIXIMAB
Common Name English
Immunoglobulin G1, anti-(human claudin-18.2) (human-Mus musculus monoclonal IMAB362 heavy chain), disulfide with human-Mus musculus monoclonal IMAB362 κ-chain, dimer
Common Name English
Immunoglobulin G1-kappa, anti-[Homo sapiens CLDN18 (claudin 18, claudin-18, SFTPJ, surfactant associated protein J) isoform 2, extracellular domain 1 (EC1)], chimeric monoclonal antibody; gamma1 heavy chain (1-448) [Mus musculus VH (IGHV1-61*01 (92.90%)
Common Name English
IMAB-362
Code English
zolbetuximab [INN]
Common Name English
IMAB362
Code English
ZOLBETUXIMAB [JAN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C20401
Created by admin on Sat Dec 16 14:53:04 GMT 2023 , Edited by admin on Sat Dec 16 14:53:04 GMT 2023
NCI_THESAURUS C129822
Created by admin on Sat Dec 16 14:53:04 GMT 2023 , Edited by admin on Sat Dec 16 14:53:04 GMT 2023
FDA ORPHAN DRUG 383312
Created by admin on Sat Dec 16 14:53:04 GMT 2023 , Edited by admin on Sat Dec 16 14:53:04 GMT 2023
Code System Code Type Description
CAS
1496553-00-4
Created by admin on Sat Dec 16 14:53:04 GMT 2023 , Edited by admin on Sat Dec 16 14:53:04 GMT 2023
PRIMARY
INN
10473
Created by admin on Sat Dec 16 14:53:04 GMT 2023 , Edited by admin on Sat Dec 16 14:53:04 GMT 2023
PRIMARY
DRUG BANK
DB15118
Created by admin on Sat Dec 16 14:53:04 GMT 2023 , Edited by admin on Sat Dec 16 14:53:04 GMT 2023
PRIMARY
WIKIPEDIA
Zolbetuximab
Created by admin on Sat Dec 16 14:53:04 GMT 2023 , Edited by admin on Sat Dec 16 14:53:04 GMT 2023
PRIMARY
NCI_THESAURUS
C85475
Created by admin on Sat Dec 16 14:53:04 GMT 2023 , Edited by admin on Sat Dec 16 14:53:04 GMT 2023
PRIMARY
USAN
KL-138
Created by admin on Sat Dec 16 14:53:04 GMT 2023 , Edited by admin on Sat Dec 16 14:53:04 GMT 2023
PRIMARY
FDA UNII
TF5MPQ8WGY
Created by admin on Sat Dec 16 14:53:04 GMT 2023 , Edited by admin on Sat Dec 16 14:53:04 GMT 2023
PRIMARY
CHEMBL
CHEMBL2109427
Created by admin on Sat Dec 16 14:53:04 GMT 2023 , Edited by admin on Sat Dec 16 14:53:04 GMT 2023
PRIMARY
From To
4_140 4_200
3_140 3_200
4_23 4_94
3_23 3_94
2_368 2_426
1_368 1_426
2_262 2_322
1_262 1_322
1_230 2_230
1_227 2_227
2_221 4_220
1_221 3_220
2_145 2_201
1_145 1_201
2_22 2_96
1_22 1_96
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_298
N 2_298
Related Record Type Details
CLAUDIN 18 SPLICE VARIANT 2
TARGET -> INHIBITOR
Related Record Type Details
Zolbetuximab
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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