U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C20H6Br4O5.2Na
Molecular Weight 691.854
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ACID RED 87

SMILES

[Na+].[Na+].[O-]C(=O)C1=CC=CC=C1C2=C3C=C(Br)C(=O)C(Br)=C3OC4=C(Br)C([O-])=C(Br)C=C24

InChI

InChIKey=SEACYXSIPDVVMV-UHFFFAOYSA-L
InChI=1S/C20H8Br4O5.2Na/c21-11-5-9-13(7-3-1-2-4-8(7)20(27)28)10-6-12(22)17(26)15(24)19(10)29-18(9)14(23)16(11)25;;/h1-6,25H,(H,27,28);;/q;2*+1/p-2

HIDE SMILES / InChI

Molecular Formula C20H6Br4O5
Molecular Weight 645.875
Charge -2
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
MOL RATIO 2 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Acid Red 87, also known as Eosin Y, used as an acidic red stain for cell cytoplasm and as a background stain, thereby giving contrast to the nuclear stains. In histopathology, it is applied as a counterstain after hematoxylin and before methylene blue. Acid Red 87 is also a dye photosensitizer that catalyzes electron-transfer reaction for efficient regeneration of NADH through a photosensitizer-electron relay dyad. Recently was shown that the combination of eosin Y with light-emitting diode produced bacterial inactivation, being a potential candidate for photodynamic inactivation.

Approval Year

PubMed

Sample Use Guides

In Vitro Use Guide
Bacteria (107 CFU per ml) were incubated with eosin Y (ACID RED 87) at concentrations ranging from 0·1 to 10 μmol l-1 , irradiated by green LED (λmax 490-570 nm) for 5, 10 and 15 min and the cellular viability was determined. Pseudomonas aeruginosa was completely inactivated when treated with 10 μmol l-1 eosin Y for 10 min.
Substance Class Chemical
Record UNII
TDQ283MPCW
Record Status Validated (UNII)
Record Version