TOLPROPAMINE

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NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C18H23N
Molecular Weight	253.3819
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TOLPROPAMINE

Structure Search

SMILES

CN(C)CCC(C1=CC=CC=C1)C2=CC=C(C)C=C2

InChI

InChIKey=CINROOONPHQHPO-UHFFFAOYSA-N

InChI=1S/C18H23N/c1-15-9-11-17(12-10-15)18(13-14-19(2)3)16-7-5-4-6-8-16/h4-12,18H,13-14H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C18H23N
Molecular Weight	253.3819
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: http://www.hmdb.ca/metabolites/HMDB0240238 | https://www.drugfuture.com/chemdata/tolpropamine.html

TOLPROPAMINE is an alkylamine H1-antihistamine used as an antipruritic and topical antihistaminic.

Approval Year

PubMed

PubMed

Title	Date	PubMed
[Antimycobacterial antihistaminics].	1989 Aug	2513793
Chemistry of dicationic electrophiles: superacid-catalyzed reactions of amino acetals.	2002 Jul 12	12098332

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:26:41 UTC 2023` Edited by `admin` on `Fri Dec 15 16:26:41 UTC 2023`
Record UNII	TBZ8909KFS
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TOLPROPAMINE

Official Name

English

(±)-N,N-DIMETHYL-3-PHENYL-3-P-TOLYLPROPYLAMINE

Common Name

English

tolpropamine [INN]

Common Name

English

TOLPROPAMINE [MI]

Common Name

English

Tolpropamine [WHO-DD]

Common Name

English

N,N-DIMETHYL-3-PHENYL-3-P-TOLYLPROPYLAMINE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29578

Created by admin on Fri Dec 15 16:26:41 UTC 2023 , Edited by admin on Fri Dec 15 16:26:41 UTC 2023

WHO-ATC

D04AA12

Created by admin on Fri Dec 15 16:26:41 UTC 2023 , Edited by admin on Fri Dec 15 16:26:41 UTC 2023

WHO-VATC

QD04AA12

Created by admin on Fri Dec 15 16:26:41 UTC 2023 , Edited by admin on Fri Dec 15 16:26:41 UTC 2023

Code System Code Type Description

NCI_THESAURUS

C90861

Created by admin on Fri Dec 15 16:26:41 UTC 2023 , Edited by admin on Fri Dec 15 16:26:41 UTC 2023

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FDA UNII

TBZ8909KFS

Created by admin on Fri Dec 15 16:26:41 UTC 2023 , Edited by admin on Fri Dec 15 16:26:41 UTC 2023

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MERCK INDEX

m10952

Created by admin on Fri Dec 15 16:26:41 UTC 2023 , Edited by admin on Fri Dec 15 16:26:41 UTC 2023

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Merck Index

ECHA (EC/EINECS)

227-071-2

Created by admin on Fri Dec 15 16:26:41 UTC 2023 , Edited by admin on Fri Dec 15 16:26:41 UTC 2023

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DRUG CENTRAL

3618

Created by admin on Fri Dec 15 16:26:41 UTC 2023 , Edited by admin on Fri Dec 15 16:26:41 UTC 2023

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PUBCHEM

72141

Created by admin on Fri Dec 15 16:26:41 UTC 2023 , Edited by admin on Fri Dec 15 16:26:41 UTC 2023

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EPA CompTox

DTXSID30863584

Created by admin on Fri Dec 15 16:26:41 UTC 2023 , Edited by admin on Fri Dec 15 16:26:41 UTC 2023

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EVMPD

SUB11176MIG

Created by admin on Fri Dec 15 16:26:41 UTC 2023 , Edited by admin on Fri Dec 15 16:26:41 UTC 2023

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WIKIPEDIA

TOLPROPAMINE

Created by admin on Fri Dec 15 16:26:41 UTC 2023 , Edited by admin on Fri Dec 15 16:26:41 UTC 2023

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INN

1346

Created by admin on Fri Dec 15 16:26:41 UTC 2023 , Edited by admin on Fri Dec 15 16:26:41 UTC 2023

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DRUG BANK

DB13305

Created by admin on Fri Dec 15 16:26:41 UTC 2023 , Edited by admin on Fri Dec 15 16:26:41 UTC 2023

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ChEMBL

CHEMBL2107261

Created by admin on Fri Dec 15 16:26:41 UTC 2023 , Edited by admin on Fri Dec 15 16:26:41 UTC 2023

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SMS_ID

100000077784

Created by admin on Fri Dec 15 16:26:41 UTC 2023 , Edited by admin on Fri Dec 15 16:26:41 UTC 2023

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MESH

C005547

Created by admin on Fri Dec 15 16:26:41 UTC 2023 , Edited by admin on Fri Dec 15 16:26:41 UTC 2023

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CAS

5632-44-0

Created by admin on Fri Dec 15 16:26:41 UTC 2023 , Edited by admin on Fri Dec 15 16:26:41 UTC 2023

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Related Record Type Details


					1P6C450YET

TOLPROPAMINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Related Record Type Details


					TBZ8909KFS

ACTIVE MOIETY