DORGENMELTUCEL-L (HAM-2)

Substance Class	Structurally Diverse Created by `admin` on `Mon Mar 31 22:39:02 GMT 2025` Edited by `admin` on `Mon Mar 31 22:39:02 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	ALLOGENIC HUMAN
Source Materials State	LIVE ATTENUATED GENETICALLY MODIFIED
Source Materials Parent	`7RA5N60R63` HUMAN MELANOMA CELL LINE-2 (UNMODIFIED CELL LINE USED IN DORGENMELTUCEL-L)
Part	whole
Fraction Material Type	cells
Record UNII	TBI5QC4YB6
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

Common Name

English

HUMAN MELANOMA CELL LINE-2, 1-3-ALPHA-GAL EPITOPE EXPRESSED IRRADIATED CELL VACCINE

Preferred Name

English

HYPERACUTE MELANOMA-2 (1-3-ALPHA-GAL EPITOPE EXPRESSED) IRRADIATED CELL VACCINE

Common Name

English

HYPERACUTE MELANOMA (HAM2) VACCINE IRRADIATED CELLS

Common Name

English

HYPERACUTE MELANOMA (HAM2) IRRADIATED CELL VACCINE

Common Name

English

NLG-12036 (HAM2)

Common Name

English

Code System Code Type Description

FDA UNII

TBI5QC4YB6

Created by admin on Mon Mar 31 22:39:02 GMT 2025 , Edited by admin on Mon Mar 31 22:39:02 GMT 2025

PRIMARY

Related Record Type Details


					TBI5QC4YB6

ACTIVE MOIETY

Modification Process	Modification Role	Modification Type	Amount	Fragment Name	Fragment ID
	GENE TRANSDUCTION	RETROVIRAL EXPRESSION VECTOR		MOLONEY MURINE LEUKEMIA VIRUS (MOMLV)-BASED RETROVIRAL VECTOR EXPRESSING THE MURINE ALPHA(1,3)GALACTOSYL TRANSFERASE GENE	PKN4439U0A
	GLYCOSYLATION ENZYME	EXPRESSED ENZYME		ALPHA-1,3-GALACTOSYLTRANSFERASE (MURINE)	2VR2NG1868

Modification Role	Parameter Name	Amount
Inactivation	IRRADIATION

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
VECTOR EXPRESSED EPITOPE					ALPHA-1,3-GAL EPITOPE	7L406759L8