PENTAFLUOROPROPANE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C3H3F5
Molecular Weight	134.0479
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

FC(F)CC(F)(F)F

InChI

InChIKey=MSSNHSVIGIHOJA-UHFFFAOYSA-N

InChI=1S/C3H3F5/c4-2(5)1-3(6,7)8/h2H,1H2

HIDE SMILES / InChI

Molecular Formula	C3H3F5
Molecular Weight	134.0479
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/23332645 | https://www.ncbi.nlm.nih.gov/pubmed/12018995

1,1,1,3,3-Pentafluoropropane (or pentafluoropropane, or HFC-245fa), a chlorofluorocarbon substitute, is used primarily for spray foam insulation. Pentafluoropropane is metabolized in human with the formation of the minor, but highly toxic metabolite 3,3,3-trifluoropropanoic acid.

Approval Year

PubMed

Title	Date	PubMed
Unexpected brain lesions in lactating Sprague-Dawley rats in a Two-generation Inhalation Reproductive Toxicity Study with pentafluoropropane (HFC-245fa).	2013-09	23332645
Biotransformation of 1,1,1,3,3-Pentafluoropropane (HFC-245fa).	2002-05	12018995

Sample Use Guides

In Vivo Use Guide

Sprague-Dawley rats were exposed to 2000, 10,000 and 50,000 ppm of HFC-245fa (pentafluoropropane)

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Wed Apr 02 17:59:22 GMT 2025` Edited by `admin` on `Wed Apr 02 17:59:22 GMT 2025`
Record UNII	TA9UOF49CY
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ENOVATE 3000

Preferred Name

English

PENTAFLUOROPROPANE

Official Name

English

Pentafluoropropane [WHO-DD]

Common Name

English

PENTAFLUOROPROPANE [MART.]

Common Name

English

1,1,1,3,3-PENTAFLUOROPROPANE

Systematic Name

English

HFC-245A

Code

English

HFC245A

Code

English

PENTAFLUOROPROPANE [VANDF]

Common Name

English

HFC 245A

Code

English

Code System Code Type Description

SMS_ID

100000145051