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Details

Stereochemistry ACHIRAL
Molecular Formula C3H3F5
Molecular Weight 134.0479
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PENTAFLUOROPROPANE

SMILES

FC(F)CC(F)(F)F

InChI

InChIKey=MSSNHSVIGIHOJA-UHFFFAOYSA-N
InChI=1S/C3H3F5/c4-2(5)1-3(6,7)8/h2H,1H2

HIDE SMILES / InChI
Molecular Formula C3H3F5
Molecular Weight 134.0479
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

1,1,1,3,3-Pentafluoropropane (or pentafluoropropane, or HFC-245fa), a chlorofluorocarbon substitute, is used primarily for spray foam insulation. Pentafluoropropane is metabolized in human with the formation of the minor, but highly toxic metabolite 3,3,3-trifluoropropanoic acid.

Approval Year

2014
494
PubMed

PubMed

TitleDatePubMed
Biotransformation of 1,1,1,3,3-Pentafluoropropane (HFC-245fa).
2002 May
Unexpected brain lesions in lactating Sprague-Dawley rats in a Two-generation Inhalation Reproductive Toxicity Study with pentafluoropropane (HFC-245fa).
2013 Sep

Sample Use Guides

In Vivo Use Guide
Curator's Comment: rats
Sprague-Dawley rats were exposed to 2000, 10,000 and 50,000 ppm of HFC-245fa (pentafluoropropane)
Route of Administration: Other
Substance Class Chemical
Created
by admin
on Sat Dec 16 20:00:13 UTC 2023
Edited
by admin
on Sat Dec 16 20:00:13 UTC 2023
Record UNII
TA9UOF49CY
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PENTAFLUOROPROPANE
INCI   MART.   VANDF   WHO-DD  
INCI  
Official Name English
Pentafluoropropane [WHO-DD]
Common Name English
PENTAFLUOROPROPANE [MART.]
Common Name English
1,1,1,3,3-PENTAFLUOROPROPANE
Systematic Name English
HFC-245A
Code English
HFC245A
Code English
PENTAFLUOROPROPANE [INCI]
Common Name English
PENTAFLUOROPROPANE [VANDF]
Common Name English
ENOVATE 3000
Brand Name English
HFC 245A
Code English
Code System Code Type Description
SMS_ID
100000145051
Created by admin on Sat Dec 16 20:00:13 UTC 2023 , Edited by admin on Sat Dec 16 20:00:13 UTC 2023
PRIMARY
WIKIPEDIA
PENTAFLUOROPROPANE
Created by admin on Sat Dec 16 20:00:13 UTC 2023 , Edited by admin on Sat Dec 16 20:00:13 UTC 2023
PRIMARY
CAS
460-73-1
Created by admin on Sat Dec 16 20:00:13 UTC 2023 , Edited by admin on Sat Dec 16 20:00:13 UTC 2023
PRIMARY
DAILYMED
TA9UOF49CY
Created by admin on Sat Dec 16 20:00:13 UTC 2023 , Edited by admin on Sat Dec 16 20:00:13 UTC 2023
PRIMARY
MESH
C403631
Created by admin on Sat Dec 16 20:00:13 UTC 2023 , Edited by admin on Sat Dec 16 20:00:13 UTC 2023
PRIMARY
EVMPD
SUB122641
Created by admin on Sat Dec 16 20:00:13 UTC 2023 , Edited by admin on Sat Dec 16 20:00:13 UTC 2023
PRIMARY
EPA CompTox
DTXSID6052110
Created by admin on Sat Dec 16 20:00:13 UTC 2023 , Edited by admin on Sat Dec 16 20:00:13 UTC 2023
PRIMARY
DRUG BANK
DB13117
Created by admin on Sat Dec 16 20:00:13 UTC 2023 , Edited by admin on Sat Dec 16 20:00:13 UTC 2023
PRIMARY
RXCUI
1591891
Created by admin on Sat Dec 16 20:00:13 UTC 2023 , Edited by admin on Sat Dec 16 20:00:13 UTC 2023
PRIMARY RxNorm
PUBCHEM
68030
Created by admin on Sat Dec 16 20:00:13 UTC 2023 , Edited by admin on Sat Dec 16 20:00:13 UTC 2023
PRIMARY
EVMPD
SUB127324
Created by admin on Sat Dec 16 20:00:13 UTC 2023 , Edited by admin on Sat Dec 16 20:00:13 UTC 2023
PRIMARY
FDA UNII
TA9UOF49CY
Created by admin on Sat Dec 16 20:00:13 UTC 2023 , Edited by admin on Sat Dec 16 20:00:13 UTC 2023
PRIMARY
NIH
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