DMT-2'-Fluoro-dG(Ib) Phosphoramidite

Details

Stereochemistry	EPIMERIC
Molecular Formula	C44H53FN7O8P
Molecular Weight	857.9059
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DMT-2'-Fluoro-dG(Ib) Phosphoramidite

Structure Search

SMILES

COC1=CC=C(C=C1)C(OC[C@H]2O[C@H]([C@H](F)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C=NC4=C3NC(NC(=O)C(C)C)=NC4=O)(C5=CC=CC=C5)C6=CC=C(OC)C=C6

InChI

InChIKey=KJFUMXZZVYMQEU-AOCJBPQJSA-N

InChI=1S/C44H53FN7O8P/c1-27(2)40(53)49-43-48-39-37(41(54)50-43)47-26-51(39)42-36(45)38(60-61(58-24-12-23-46)52(28(3)4)29(5)6)35(59-42)25-57-44(30-13-10-9-11-14-30,31-15-19-33(55-7)20-16-31)32-17-21-34(56-8)22-18-32/h9-11,13-22,26-29,35-36,38,42H,12,24-25H2,1-8H3,(H2,48,49,50,53,54)/t35-,36-,38-,42-,61?/m1/s1

HIDE SMILES / InChI

Molecular Formula	C44H53FN7O8P
Molecular Weight	857.9059
Charge	0
Count

Stereochemistry	EPIMERIC
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Wed Apr 02 20:34:31 GMT 2025` Edited by `admin` on `Wed Apr 02 20:34:31 GMT 2025`
Record UNII	T97KRQ76SF
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2'-fluoro-N2-isobutyryl-5'-O-(4, 4'-dimethoxytrityl)-2'-deoxyguanosine-3'-CE-Phosphoramidite

Preferred Name

English

DMT-2'-Fluoro-dG(Ib) Phosphoramidite

Common Name

English

(2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluoro-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

Systematic Name

English

5'-O-DMT-2'-fluoro-N2-isobutyryl-2'-Deoxy-guanosine 3'-CE phosphoramidite

Common Name

English

N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-[2-cyanoethoxy-(diisopropylamino)phosphanyl]oxy-3-fluoro-tetrahydrofuran-2-yl]-6-oxo-3H-purin-2-yl]-2-methyl-propanamide

Systematic Name

English

Guanosine, 5?-O-[bis(4-methoxyphenyl)phenylmethyl]-2?-deoxy-2?-fluoro-N-(2-methyl-1-oxopropyl)-, 3?-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

Common Name

English

Guanosine, 5?-O-[bis(4-methoxyphenyl)phenylmethyl]-2?-deoxy-2?-fluoro-N-(2-methyl-1-oxopropyl)-, 3?-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

Common Name

English

Code System Code Type Description

FDA UNII

T97KRQ76SF

Created by admin on Wed Apr 02 20:34:31 GMT 2025 , Edited by admin on Wed Apr 02 20:34:31 GMT 2025

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CAS

144089-97-4

Created by admin on Wed Apr 02 20:34:31 GMT 2025 , Edited by admin on Wed Apr 02 20:34:31 GMT 2025

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PUBCHEM

135448972

Created by admin on Wed Apr 02 20:34:31 GMT 2025 , Edited by admin on Wed Apr 02 20:34:31 GMT 2025

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