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Details

Stereochemistry ABSOLUTE
Molecular Formula C10H16FN2O14P3
Molecular Weight 500.1587
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PSI-7409

SMILES

C[C@@]1(F)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1N2C=CC(=O)NC2=O

InChI

InChIKey=IPHULAIUXUVCHH-VPCXQMTMSA-N
InChI=1S/C10H16FN2O14P3/c1-10(11)7(15)5(25-8(10)13-3-2-6(14)12-9(13)16)4-24-29(20,21)27-30(22,23)26-28(17,18)19/h2-3,5,7-8,15H,4H2,1H3,(H,20,21)(H,22,23)(H,12,14,16)(H2,17,18,19)/t5-,7-,8-,10-/m1/s1

HIDE SMILES / InChI

Molecular Formula C10H16FN2O14P3
Molecular Weight 500.1587
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Characterization of the metabolic activation of hepatitis C virus nucleoside inhibitor beta-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine (PSI-6130) and identification of a novel active 5'-triphosphate species.
2007 Oct 12
PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication.
2010 Aug
Substance Class Chemical
Created
by admin
on Sat Dec 16 10:46:27 UTC 2023
Edited
by admin
on Sat Dec 16 10:46:27 UTC 2023
Record UNII
T90A75S60M
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PSI-7409
Common Name English
DIHYDROXYPHOSPHORYL (((2R,3R,4R,5R)-5-(2,4-DIOXOPYRIMIDIN-1-YL)-4-FLUORO-3-HYDROXY-4-METHYL-TETRAHYDROFURAN-2-YL)METHOXY-HYDROXY-PHOSPHORYL) HYDROGEN PHOSPHATE
Systematic Name English
URIDINE 5'-(TETRAHYDROGEN TRIPHOSPHATE), 2'-DEOXY-2'-FLUORO-2'-METHYL-, (2'R)-
Common Name English
GS-461203
Common Name English
Code System Code Type Description
CAS
1015073-42-3
Created by admin on Sat Dec 16 10:46:28 UTC 2023 , Edited by admin on Sat Dec 16 10:46:28 UTC 2023
PRIMARY
FDA UNII
T90A75S60M
Created by admin on Sat Dec 16 10:46:28 UTC 2023 , Edited by admin on Sat Dec 16 10:46:28 UTC 2023
PRIMARY
PUBCHEM
23725128
Created by admin on Sat Dec 16 10:46:28 UTC 2023 , Edited by admin on Sat Dec 16 10:46:28 UTC 2023
PRIMARY
Related Record Type Details
PRODRUG -> METABOLITE ACTIVE
MINOR
Related Record Type Details
ACTIVE MOIETY