TECHNETIUM TC-99M TIATIDE

First approved in 1973

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H12N3O5S.O.Tc
Molecular Weight	377.169
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[O--].[99Tc+3].[O-]C(=O)CNC(=O)CNC(=O)CNC(=O)CS

InChI

InChIKey=HYENJUTYRRNRJB-FCHARDOESA-M

InChI=1S/C8H13N3O5S.O.Tc/c12-5(2-10-7(14)4-17)9-1-6(13)11-3-8(15)16;;/h17H,1-4H2,(H,9,12)(H,10,14)(H,11,13)(H,15,16);;/q;-2;+3/p-1/i;;1+1

HIDE SMILES / InChI

Molecular Formula	HO
Molecular Weight	17.0073
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C8H12N3O5S
Molecular Weight	262.263
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Tc
Molecular Weight	98.9063
Charge	3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.hindawi.com/journals/stni/2014/839369/
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401

Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2578
bone problems 43 Sources: https://www.drugs.com/cons/osteolite.html	Diagnostic	Approved 8429	OSTEOLITE Approved Use Unknown Launch Date 1977
osteogenesis 43 Sources: https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018035s032lbl.pdf	Diagnostic	Approved 8429	DRAXIMAGE MDP-10 Approved Use MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis. Launch Date 1978

PubMed

Title	Date	PubMed
Future of low specific activity molybdenum-99/technetium-99m generator.	2012 Oct	22642420

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:25:53 GMT 2023` Edited by `admin` on `Fri Dec 15 16:25:53 GMT 2023`
Record UNII	T8S697S62F
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TECHNETIUM TC-99M TIATIDE

Common Name

English

99MTC-MAG3

Brand Name

English

GLYCINE, N-(N-(N-(MERCAPTOACETYL)GLYCYL)GLYCYL)-, TECHNETIUM-99 COMPLEX

Common Name

English

TECHNETATE(2-)-99TC, (N-(N-(N-(MERCAPTOACETYL)GLYCYL)GLYCYL)GLYCINATO(5-)-N,N',N'',S)OXO-, (SP-5-25)-

Common Name

English

TECHNETATE(2-)-99TC, ((MERCAPTO-.KAPPA.S)ACETYLGLYCYL-.KAPPA.N-GLYCYL-.KAPPA.N-GLYCINATO(5-)-.KAPPA.N)OXO-, (SP-5-25)-

Common Name

English

TECHNETIUM TC 99M TIATIDE

Common Name

English

TECHNETIUM TC 99M MERTIATIDE ANION [MI]

Common Name

English

TECHNETIUM TC-99M TIATIDE (ANION)

Common Name

English

TECHNETATE(2-)-99TC, (2-(MERCAPTO-.KAPPA.S)ACETYLGLYCYL-.KAPPA.N-GLYCYL-.KAPPA.N-GLYCINATO(5-)-.KAPPA.N)OXO-, (SP-5-25)-

Common Name

English

Technetium tc 99m tiatide [WHO-DD]

Common Name

English

Code System Code Type Description

MERCK INDEX

m10508