EVINACUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 22:06:36 GMT 2025` Edited by `admin` on `Mon Mar 31 22:06:36 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	T8B2ORP1DW
Record Status	`Validated (UNII)`
Record Version

Download

Related Record	Type

Name

Type

Language

evinacumab [INN]

Preferred Name

English

EVINACUMAB

Official Name

English

REGN-1500

Code

English

REGN1500

Code

English

IMMUNOGLOBULIN G4, ANTI-(HUMAN PROTEIN ANGPTL3 (ANGIOPOIETIN-LIKE 3)) (HUMAN MONOCLONAL REGN1500 HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL REGN1500 LIGHT CHAIN, DIMER

Common Name

English

EVINACUMAB [USAN]

Common Name

English

Evinacumab [WHO-DD]

Common Name

English

EVINACUMAB [JAN]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

507815

Created by admin on Mon Mar 31 22:06:36 GMT 2025 , Edited by admin on Mon Mar 31 22:06:36 GMT 2025

Code System Code Type Description

ChEMBL

CHEMBL3545191

Created by admin on Mon Mar 31 22:06:36 GMT 2025 , Edited by admin on Mon Mar 31 22:06:36 GMT 2025

PRIMARY

WIKIPEDIA

Evinacumab

Created by admin on Mon Mar 31 22:06:36 GMT 2025 , Edited by admin on Mon Mar 31 22:06:36 GMT 2025

PRIMARY

NCI_THESAURUS

C169973

Created by admin on Mon Mar 31 22:06:36 GMT 2025 , Edited by admin on Mon Mar 31 22:06:36 GMT 2025

PRIMARY

SMS_ID

100000183292

Created by admin on Mon Mar 31 22:06:36 GMT 2025 , Edited by admin on Mon Mar 31 22:06:36 GMT 2025

PRIMARY

DAILYMED

T8B2ORP1DW

Created by admin on Mon Mar 31 22:06:36 GMT 2025 , Edited by admin on Mon Mar 31 22:06:36 GMT 2025

PRIMARY

DRUG BANK

DB15354

Created by admin on Mon Mar 31 22:06:36 GMT 2025 , Edited by admin on Mon Mar 31 22:06:36 GMT 2025

PRIMARY

RXCUI

2478335

Created by admin on Mon Mar 31 22:06:36 GMT 2025 , Edited by admin on Mon Mar 31 22:06:36 GMT 2025

PRIMARY

INN

10013

Created by admin on Mon Mar 31 22:06:36 GMT 2025 , Edited by admin on Mon Mar 31 22:06:36 GMT 2025

PRIMARY

USAN

BC-26

Created by admin on Mon Mar 31 22:06:36 GMT 2025 , Edited by admin on Mon Mar 31 22:06:36 GMT 2025

PRIMARY

CAS

1446419-85-7

Created by admin on Mon Mar 31 22:06:36 GMT 2025 , Edited by admin on Mon Mar 31 22:06:36 GMT 2025

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FDA UNII

T8B2ORP1DW

Created by admin on Mon Mar 31 22:06:36 GMT 2025 , Edited by admin on Mon Mar 31 22:06:36 GMT 2025

PRIMARY

From	To
1_22	1_96
1_140	3_214
1_153	1_209
1_232	2_232
1_235	2_235
1_267	1_327
1_373	1_431
2_22	2_96
2_140	4_214
2_153	2_209
2_267	2_327
2_373	2_431
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194

Glycosylation Link Type	Site
N	1_303
N	2_303

Related Record Type Details


					WKQ0PJ4VMZ

ANGIOPOIETIN-RELATED PROTEIN 3

TARGET -> INHIBITOR

Amount:

EVINACUMAB-DGNB

SUB_CONCEPT->SUBSTANCE

Amount:

Related Record Type Details


					T8B2ORP1DW

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL