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Details

Stereochemistry ACHIRAL
Molecular Formula C21H25NO2
Molecular Weight 323.4287
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1-(-2-PHENETHYL)-4-PHENYL-4-ACETOXYPIPERIDINE

SMILES

CC(=O)OC1(CCN(CCC2=CC=CC=C2)CC1)C3=CC=CC=C3

InChI

InChIKey=BVURVTVDNWSNFN-UHFFFAOYSA-N
InChI=1S/C21H25NO2/c1-18(23)24-21(20-10-6-3-7-11-20)13-16-22(17-14-21)15-12-19-8-4-2-5-9-19/h2-11H,12-17H2,1H3

HIDE SMILES / InChI
Molecular Formula C21H25NO2
Molecular Weight 323.4287
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

4-Piperidinol, 1-phenethyl-4-phenyl acetate (PEPAP) is a synthetic opioid discovered by Janssen in 1960. PEPAP is an analog of meperidine, it is abused and illegally sold on streets as a "synthetic heroin".

CNS Activity

CNS Active
3913
Curator's Comment: Known to be CNS active in mice. Drug of abuse.

Originator

Approval Year

Unknown
139594
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Preclinical
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed

Sample Use Guides

In Vivo Use Guide
In a "hot plate" method compound was injected into mice subcutaneously. EC50 in the test was 6.9 ug/kg
Route of Administration: Other
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 18:14:37 GMT 2023
Edited
by admin
on Fri Dec 15 18:14:37 GMT 2023
Record UNII
T6LN72I828
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
1-(-2-PHENETHYL)-4-PHENYL-4-ACETOXYPIPERIDINE
Systematic Name English
4-PIPERIDINOL, 1-PHENETHYL-4-PHENYL-, ACETATE (ESTER)
Common Name English
1-(2-PHENYLETHYL)-4-PHENYL-4-ACETOXYPIPERIDINE
Systematic Name English
4-PIPERIDINOL, 4-PHENYL-1-(2-PHENYLETHYL)-, ACETATE (ESTER)
Common Name English
MCV 4527
Code English
PEPAP
Common Name English
NIH 10460
Code English
IDS-NP-026
Code English
IDS-NP-026(SECT.3)
Code English
1-PHENETHYL-4-PHENYL-4-PIPERIDINOL ACETATE(ESTER)
Common Name English
Classification Tree Code System Code
DEA NO. 9663
Created by admin on Fri Dec 15 18:14:37 GMT 2023 , Edited by admin on Fri Dec 15 18:14:37 GMT 2023
YELLOW LIST NP 026
Created by admin on Fri Dec 15 18:14:37 GMT 2023 , Edited by admin on Fri Dec 15 18:14:37 GMT 2023
Code System Code Type Description
WIKIPEDIA
PEPAP
Created by admin on Fri Dec 15 18:14:37 GMT 2023 , Edited by admin on Fri Dec 15 18:14:37 GMT 2023
PRIMARY PEPAP (Phenethylphenylacetoxypiperidine) is an opioid analgesic that is an analog of pethidine (meperidine).It is related to the drug MPPP, with an N-phenethyl group in place of the N-methyl substitution and an acetate ester rather than propionate.
CAS
64-52-8
Created by admin on Fri Dec 15 18:14:37 GMT 2023 , Edited by admin on Fri Dec 15 18:14:37 GMT 2023
PRIMARY
DRUG BANK
DB01562
Created by admin on Fri Dec 15 18:14:37 GMT 2023 , Edited by admin on Fri Dec 15 18:14:37 GMT 2023
PRIMARY
PUBCHEM
60977
Created by admin on Fri Dec 15 18:14:37 GMT 2023 , Edited by admin on Fri Dec 15 18:14:37 GMT 2023
PRIMARY
EPA CompTox
DTXSID5048922
Created by admin on Fri Dec 15 18:14:37 GMT 2023 , Edited by admin on Fri Dec 15 18:14:37 GMT 2023
PRIMARY
FDA UNII
T6LN72I828
Created by admin on Fri Dec 15 18:14:37 GMT 2023 , Edited by admin on Fri Dec 15 18:14:37 GMT 2023
PRIMARY
Related Record Type Details
Structure of 1-(-2-PHENETHYL)-4-PHENYL-4-ACETOXYPIPERIDINE HYDROCHLORIDE
SALT/SOLVATE -> PARENT
APPROXIMATE PURE ANHYDROUS DRUG CONTENT (IN PERCENT)
NIH
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