HYPOCHLORITE ION

Possibly Marketed Outside US

First approved in 1983

Details

Stereochemistry	ACHIRAL
Molecular Formula	ClO
Molecular Weight	51.452
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	-1

SHOW SMILES / InChI

Structure Search

SMILES

[O-]Cl

InChI

InChIKey=WQYVRQLZKVEZGA-UHFFFAOYSA-N

InChI=1S/ClO/c1-2/q-1

HIDE SMILES / InChI

Molecular Formula	ClHO
Molecular Weight	52.46
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/mesh/68006997 | https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=3d72b72c-2949-4eb6-b64c-6c4aef0eddd9&type=display

HYPOCHLORITE (as sodium salt) is a main active component of DAKIN'S® antimicrobial solution, which is used to prevent and treat infections of the skin and tissue, and also pre- and post-surgery cuts, abrasions, and skin ulcers.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Tinea pedis 28 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b250f4a4-6fdf-4a91-b214-4447aec3bb33	Curative		Approved 8583	FUNGOID TINCTURE TREATMENT KIT- Approved Use Cures most athlete's foot (tinea pedis) and ringworm (tinea corporis). For effective relief of itchy, scaly skin between the toes

PubMed

Title	Date	PubMed
Anatomy of sodium hypochlorite accidents.	2007-10	18018389
Review: the use of sodium hypochlorite in endodontics--potential complications and their management.	2007-05-12	17496870
Sodium dichloroisocyanurate (NaDCC) tablets as an alternative to sodium hypochlorite for the routine treatment of drinking water at the household level.	2006-03	16387550
[Use of sodium hypochlorite in surgery].	2005-07-20	16025672
Hypochlorite-induced oxidation of amino acids, peptides and proteins.	2003-12	14661089
Hypochlorite, oxidative modification of plasma lipoproteins, and atherosclerosis.	2001-05	11550040
Fatal ingestion of sodium hypochlorite bleach with associated hypernatremia and hyperchloremic metabolic acidosis.	1999-04	10192136
[Detoxication and disinfection by sodium hypochlorite].	1999-02-09	9949989
Sodium hypochlorite and its use as an endodontic irrigant.	1998-08	9775472
Uses of inorganic hypochlorite (bleach) in health-care facilities.	1997-10	9336664
The mechanism of the hypochlorite-induced lipid peroxidation.	1997	9260000
Household bleaches based on sodium hypochlorite: review of acute toxicology and poison control center experience.	1994-09	7927083
Proposal for experimental studies to evaluate sodium hypochlorite dialysate in retroviral treatment.	1994-03	8057971
Effects of sodium hypochlorite on soft tissues after its inadvertent injection beyond the root apex.	1991-11	1812208
Re: sternal cupping.	1982-12	7146426

Patents

Sample Use Guides

In Vivo Use Guide

Apply once daily for lightly to moderately exudative wounds. Apply twice daily for highly exudative or highly contaminated wounds. Protect intact skin with a moisture barrier ointment or skin sealant as needed.

Route of Administration: Topical

Substance Class	Chemical Created by `admin` on `Mon Mar 31 20:20:11 GMT 2025` Edited by `admin` on `Mon Mar 31 20:20:11 GMT 2025`
Record UNII	T5UM7HB19N
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

HYPOCHLORITE ION

Common Name

English

HYPOCHLORITE ANION

Preferred Name

English

HYPOCHLORITE

Systematic Name

English

HYPOCHLOROUS ACID, ION(1-)

Common Name

English

Code System Code Type Description

FDA UNII

T5UM7HB19N