FLESTOLOL SULFATE

Details

Stereochemistry	RACEMIC
Molecular Formula	C15H22FN3O4.H2O4S
Molecular Weight	425.43
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OS(O)(=O)=O.CC(C)(CNC(N)=O)NCC(O)COC(=O)C1=C(F)C=CC=C1

InChI

InChIKey=QLCLNERFMKNCBZ-UHFFFAOYSA-N

InChI=1S/C15H22FN3O4.H2O4S/c1-15(2,9-18-14(17)22)19-7-10(20)8-23-13(21)11-5-3-4-6-12(11)16;1-5(2,3)4/h3-6,10,19-20H,7-9H2,1-2H3,(H3,17,18,22);(H2,1,2,3,4)

HIDE SMILES / InChI

Molecular Formula	H2O4S
Molecular Weight	98.078
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C15H22FN3O4
Molecular Weight	327.3513
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/mesh/67047847 | https://www.ncbi.nlm.nih.gov/pubmed/2870085 | https://www.ncbi.nlm.nih.gov/pubmed/2868646

FLESTOLOL is an ultra-short-acting beta-adrenergic blocking agent without any intrinsic sympathomimetic activity.

Originator

Approval Year

PubMed

Title	Date	PubMed
Flestolol: an ultra-short-acting beta-adrenergic blocking agent.	1986 Mar	2870085
Tolerance and beta-adrenergic blocking activity of flestolol, a short-acting beta blocker.	1986 May	3698462
Antiarrhythmic activity of flestolol, a novel ultra-short-acting beta-adrenoceptor antagonist, in the dog.	1986 Nov 12	2880726
Pharmacokinetics and pharmacodynamics of flestolol, a new short-acting, beta-adrenergic receptor antagonist.	1987 Jan	2890664

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:19:27 UTC 2023` Edited by `admin` on `Fri Dec 15 16:19:27 UTC 2023`
Record UNII	T5MWT8445U
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FLESTOLOL SULFATE

Official Name

English

FLESTOLOL SULPHATE

Common Name

English

O-FLUOROBENZOIC ACID, 3-ESTER WITH (±)-(2-((2,3-DIHYDROXYPROPYL)AMINO)-2-METHYLPROPYL)UREA, SULFATE (1:1) (SALT)

Common Name

English

FLESTOLOL SULFATE [MART.]

Common Name

English

ACC-9089-005

Common Name

English

BENZOIC ACID, 2-FLUORO-, 3-((2-((AMINOCARBONYL)AMINO)-1,1-DIMETHYLETHYL)AMINO)-2-HYDROXYPROPYL ESTER, (±)-, SULFATE (1:1) (SALT)

Common Name

English

FLESTOLOL SULFATE [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29576