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Details

Stereochemistry ACHIRAL
Molecular Formula Cr2O7.2K
Molecular Weight 294.1846
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of POTASSIUM DICHROMATE

SMILES

[K+].[K+].[O-][Cr](=O)(=O)O[Cr]([O-])(=O)=O

InChI

InChIKey=KMUONIBRACKNSN-UHFFFAOYSA-N
InChI=1S/2Cr.2K.7O/q;;2*+1;;;;;;2*-1

HIDE SMILES / InChI

Molecular Formula K
Molecular Weight 39.0983
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Cr2O7
Molecular Weight 215.988
Charge -2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Sodium dichromate is an inorganic compound, containing hexavalent chromium. It is highly corrosive and is a strong oxidizing agent. Sodium dichromate is mainly used to produce other chromium compounds but is also used in drilling muds, in metal treatments, in wood preservatives, in the production of dyes and organic chemicals and as a corrosion inhibitor. Sodium dichromate primarily affects the respiratory system causing ulcerations, shortness of breath, bronchitis, pneumonia, and asthma but can also affect the gastrointestinal tract, liver, kidneys and immune system. This substance is a known human carcinogen and is associated with an increased risk of developing lung cancer and cancer of the sinonasal cavity.

Approval Year

PubMed

PubMed

TitleDatePubMed
Effects of Cr(VI) on the expression of the oxidative stress genes in human lung cells.
1998 Aug
LLU-alpha, an endogenous metabolite of gamma-tocopherol, is more effective against metal nephrotoxicity in rats than gamma-tocopherol.
2001 Jul 6
Chromium (VI)-induced oxidative stress, apoptotic cell death and modulation of p53 tumor suppressor gene.
2001 Jun
Induction of apoptosis in the lung but not in the liver of rats receiving intra-tracheal instillations of chromium(VI).
2002 Apr
Down-regulation of the DNA-repair endonuclease 8-oxo-guanine DNA glycosylase 1 (hOGG1) by sodium dichromate in cultured human A549 lung carcinoma cells.
2002 Jan
Selective induction of gene expression in rat lung by hexavalent chromium.
2002 Oct
Interindividual variability in response to sodium dichromate-induced oxidative DNA damage: role of the Ser326Cys polymorphism in the DNA-repair protein of 8-oxo-7,8-dihydro-2'-deoxyguanosine DNA glycosylase 1.
2005 Feb
NTP toxicity studies of sodium dichromate dihydrate (CAS No. 7789-12-0) administered in drinking water to male and female F344/N rats and B6C3F1 mice and male BALB/c and am3-C57BL/6 mice.
2007 Jan
Identification of human cell responses to hexavalent chromium.
2007 Oct
Comparison of the preventive effect of vitamin C and E on hexavalent chromium induced pulmonary fibrosis in rat.
2008 Aug
Superoxide-mediated proteasomal degradation of Bcl-2 determines cell susceptibility to Cr(VI)-induced apoptosis.
2008 Aug
Nitric oxide-mediated bcl-2 stabilization potentiates malignant transformation of human lung epithelial cells.
2010 May
Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90days of exposure to hexavalent chromium in drinking water.
2012 Feb 15
Comparative toxicogenomic analysis of oral Cr(VI) exposure effects in rat and mouse small intestinal epithelia.
2012 Jul 15
Long-term exposure to hexavalent chromium inhibits expression of tumor suppressor genes in cultured cells and in mice.
2012 Jun
Whole adult organism transcriptional profiling of acute metal exposures in male zebrafish.
2014 Mar 10
Temporal changes in rat liver gene expression after acute cadmium and chromium exposure.
2015
Human bronchial epithelial BEAS-2B cells, an appropriate in vitro model to study heavy metals induced carcinogenesis.
2015 Sep 15
Hepatoprotective effect of Taraxacum officinale leaf extract on sodium dichromate-induced liver injury in rats.
2016 Mar
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:29:19 GMT 2023
Edited
by admin
on Fri Dec 15 16:29:19 GMT 2023
Record UNII
T4423S18FM
Record Status Validated (UNII)
Record Version
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Name Type Language
POTASSIUM DICHROMATE
HSDB   MART.   VANDF   WHO-DD  
Systematic Name English
POTASSIUM DICHROMATE [HSDB]
Common Name English
POTASSIUM DICHROMATE(VI) [MI]
Common Name English
Potassium dichromate [WHO-DD]
Common Name English
NSC-77372
Code English
POTASSIUM BICHROMATE
Common Name English
POTASSIUM DICHROMATE [MART.]
Common Name English
CHROMIC ACID (H2CR2O7) POTASSIUM SALT (1:2)
Common Name English
KALI BICHROMICUM [HPUS]
Common Name English
POTASSIUM DICHROMATE(VI)
MI  
Common Name English
KALI BICHROMICUM
HPUS  
Common Name English
POTASSIUM DICHROMATE [VANDF]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C44357
Created by admin on Fri Dec 15 16:29:19 GMT 2023 , Edited by admin on Fri Dec 15 16:29:19 GMT 2023
Code System Code Type Description
MERCK INDEX
m9018
Created by admin on Fri Dec 15 16:29:19 GMT 2023 , Edited by admin on Fri Dec 15 16:29:19 GMT 2023
PRIMARY Merck Index
PUBCHEM
24502
Created by admin on Fri Dec 15 16:29:19 GMT 2023 , Edited by admin on Fri Dec 15 16:29:19 GMT 2023
PRIMARY
DRUG BANK
DBSALT002757
Created by admin on Fri Dec 15 16:29:19 GMT 2023 , Edited by admin on Fri Dec 15 16:29:19 GMT 2023
PRIMARY
DAILYMED
T4423S18FM
Created by admin on Fri Dec 15 16:29:19 GMT 2023 , Edited by admin on Fri Dec 15 16:29:19 GMT 2023
PRIMARY
CAS
7778-50-9
Created by admin on Fri Dec 15 16:29:19 GMT 2023 , Edited by admin on Fri Dec 15 16:29:19 GMT 2023
PRIMARY
CHEBI
53444
Created by admin on Fri Dec 15 16:29:19 GMT 2023 , Edited by admin on Fri Dec 15 16:29:19 GMT 2023
PRIMARY
WIKIPEDIA
POTASSIUM DICHROMATE
Created by admin on Fri Dec 15 16:29:19 GMT 2023 , Edited by admin on Fri Dec 15 16:29:19 GMT 2023
PRIMARY
EPA CompTox
DTXSID5025948
Created by admin on Fri Dec 15 16:29:19 GMT 2023 , Edited by admin on Fri Dec 15 16:29:19 GMT 2023
PRIMARY
NCI_THESAURUS
C45890
Created by admin on Fri Dec 15 16:29:19 GMT 2023 , Edited by admin on Fri Dec 15 16:29:19 GMT 2023
PRIMARY
ECHA (EC/EINECS)
231-906-6
Created by admin on Fri Dec 15 16:29:19 GMT 2023 , Edited by admin on Fri Dec 15 16:29:19 GMT 2023
PRIMARY
SMS_ID
100000128015
Created by admin on Fri Dec 15 16:29:19 GMT 2023 , Edited by admin on Fri Dec 15 16:29:19 GMT 2023
PRIMARY
RXCUI
8595
Created by admin on Fri Dec 15 16:29:19 GMT 2023 , Edited by admin on Fri Dec 15 16:29:19 GMT 2023
PRIMARY RxNorm
HSDB
1238
Created by admin on Fri Dec 15 16:29:19 GMT 2023 , Edited by admin on Fri Dec 15 16:29:19 GMT 2023
PRIMARY
NSC
77372
Created by admin on Fri Dec 15 16:29:19 GMT 2023 , Edited by admin on Fri Dec 15 16:29:19 GMT 2023
PRIMARY
FDA UNII
T4423S18FM
Created by admin on Fri Dec 15 16:29:19 GMT 2023 , Edited by admin on Fri Dec 15 16:29:19 GMT 2023
PRIMARY
MESH
D011192
Created by admin on Fri Dec 15 16:29:19 GMT 2023 , Edited by admin on Fri Dec 15 16:29:19 GMT 2023
PRIMARY
EVMPD
SUB34566
Created by admin on Fri Dec 15 16:29:19 GMT 2023 , Edited by admin on Fri Dec 15 16:29:19 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY