TISOTUMAB VEDOTIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	T41737F88A
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TISOTUMAB VEDOTIN

Official Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN BLOOD-COAGULATION FACTOR III) (HUMAN MONOCLONAL HUMAX-TF HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL HUMAX-TF .KAPPA.-CHAIN, DIMER, TETRAKIS(THIOETHER) WITH N-(((4-((N-(6-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYL)-1-OXOHEXYL)-

Common Name

English

TISOTUMAB VEDOTIN [JAN]

Common Name

English

TISOTUMAB VEDOTIN [USAN]

Common Name

English

Tisotumab vedotin [WHO-DD]

Common Name

English

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Classification Tree

Code System

Code

Antineoplastic Biological Agent

NCI_THESAURUS

C129823

Biological Agent

NCI_THESAURUS

C20401

Antineoplastic Agent

NCI_THESAURUS

C1742

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Code System

Code

Type

Description

RXCUI

2571094

PRIMARY

DAILYMED

T41737F88A

PRIMARY

FDA UNII

T41737F88A

PRIMARY

USAN

GH-177

PRIMARY

WIKIPEDIA

Tisotumab vedotin

PRIMARY

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From	To
1_22	1_96
1_145	1_201
1_262	1_322
1_368	1_426
2_22	2_96

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Glycosylation Type

MAMMALIAN

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Related Record

Type

Details


					1U5PI2DLU1

TARGET->CONJUGATED TOXIN

Amount:


					Q3606FDE0B

VEDOTIN FRAGMENT

CONJUGATE COMPONENT->CONJUGATE

Amount:


					Q3606FDE0B

VEDOTIN FRAGMENT

CONJUGATE COMPONENT->CONJUGATE

Qualification:

DEPENDENCY

Amount:


					6603L01WUR

CYSTEINE-VC-MMAE

CONJUGATE COMPONENT->CONJUGATE

Amount:

TISOTUMAB VEDOTIN-TFTV

SUB_CONCEPT->SUBSTANCE

Amount:

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Related Record

Type

Details


					T41737F88A

TISOTUMAB VEDOTIN

ACTIVE MOIETY

Amount:

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL	ESTIMATED 145000 Da (average)
Molecular Formula	CHEMICAL	ESTIMATED C6418H9888N1710O2022S44

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