U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 10:12:43 GMT 2023
Edited
by admin
on Sat Dec 16 10:12:43 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG2
Sequence Origin MOUSE CHIMERIC
Sequence Type COMPLETE
Record UNII
T13V17U431
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
VADASTUXIMAB TALIRINE
INN   USAN   WHO-DD  
USAN   INN  
Official Name English
SGN-CD33A
Code English
SGNCD33A
Code English
vadastuximab talirine [INN]
Common Name English
Vadastuximab talirine [WHO-DD]
Common Name English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS CD33 (SIALIC ACID BINDING LG-LIKE LECTIN 3, SIGLEC3, SIGLEC-3, GP67, P67)), CHIMERIC MONOCLONAL ANTIBODY CONJUGATED TO THE PYRROLOBENZODIAZEPINE (PDB) DIMER SGD-1882 GAMMA1 HEAVY CHAIN (1-447) (MUS MUSCULUS VH
Systematic Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN SIALIC ACID-BINDING IMMUNOGLOBULIN-LIKE LECTIN 3) (HUMAN-MUS MUSCULUS MONOCLONAL H2H12EC HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL H2H12EC LIGHT CHAIN, DIMER, BIS(THIOETHER) WITH N-(6-(3-MERCAPTO-2,5-DIOXO-
Systematic Name English
VADASTUXIMAB TALIRINE [USAN]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 494515
Created by admin on Sat Dec 16 10:12:43 GMT 2023 , Edited by admin on Sat Dec 16 10:12:43 GMT 2023
NCI_THESAURUS C1512
Created by admin on Sat Dec 16 10:12:43 GMT 2023 , Edited by admin on Sat Dec 16 10:12:43 GMT 2023
NCI_THESAURUS C129823
Created by admin on Sat Dec 16 10:12:43 GMT 2023 , Edited by admin on Sat Dec 16 10:12:43 GMT 2023
Code System Code Type Description
USAN
CD-154
Created by admin on Sat Dec 16 10:12:43 GMT 2023 , Edited by admin on Sat Dec 16 10:12:43 GMT 2023
PRIMARY
DRUG BANK
DB11884
Created by admin on Sat Dec 16 10:12:43 GMT 2023 , Edited by admin on Sat Dec 16 10:12:43 GMT 2023
PRIMARY
WIKIPEDIA
Vadastuximab talirine
Created by admin on Sat Dec 16 10:12:43 GMT 2023 , Edited by admin on Sat Dec 16 10:12:43 GMT 2023
PRIMARY
CAS
1436390-64-5
Created by admin on Sat Dec 16 10:12:43 GMT 2023 , Edited by admin on Sat Dec 16 10:12:43 GMT 2023
PRIMARY
NCI_THESAURUS
C111039
Created by admin on Sat Dec 16 10:12:43 GMT 2023 , Edited by admin on Sat Dec 16 10:12:43 GMT 2023
PRIMARY
INN
9983
Created by admin on Sat Dec 16 10:12:43 GMT 2023 , Edited by admin on Sat Dec 16 10:12:43 GMT 2023
PRIMARY
FDA UNII
T13V17U431
Created by admin on Sat Dec 16 10:12:43 GMT 2023 , Edited by admin on Sat Dec 16 10:12:43 GMT 2023
PRIMARY
EVMPD
SUB182510
Created by admin on Sat Dec 16 10:12:43 GMT 2023 , Edited by admin on Sat Dec 16 10:12:43 GMT 2023
PRIMARY
From To
1_22 1_96
1_144 1_200
1_261 1_321
1_367 1_425
2_22 2_96
2_144 2_200
2_261 2_321
2_367 2_425
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
1_220 3_214
2_220 4_214
1_226 2_226
1_229 2_229
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_297
N 2_297
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL