2-METHYLIMIDAZOLE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C4H6N2
Molecular Weight	82.1038
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=NC=CN1

InChI

InChIKey=LXBGSDVWAMZHDD-UHFFFAOYSA-N

InChI=1S/C4H6N2/c1-4-5-2-3-6-4/h2-3H,1H3,(H,5,6)

HIDE SMILES / InChI

Molecular Formula	C4H6N2
Molecular Weight	82.1038
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Identification of human glutaminyl cyclase as a metalloenzyme. Potent inhibition by imidazole derivatives and heterocyclic chelators.	2003 Dec 12	14522962
[Mn2(saltmen)2Ni(pao)2(L)2](A)2 with L=pyridine, 4-picoline, 4-tert-butylpyridine, N-methylimidazole and A=ClO4-, BF4-, PF6-, ReO4-: a family of single-chain magnets.	2003 Dec 15	14658870
A new family of spin crossover complexes with a tripod ligand containing three imidazoles: synthesis, characterization, and magnetic properties of [FeIIH3LMe](NO3)2.1.5H2O, [FeIIILMe].3.5H2O, [FeIIH3LMe][FeIILMe]NO3, and [FeIIH3LMe][FeIIILMe](NO3)2 (H3LMe) = Tris[2-(((2-methylimidazol-4-yl)methylidene)amino)ethyl]amine).	2003 Nov 3	14577766
Electrospray ionization mass spectral characteristics and fragmentation mechanisms of novel photoinduced DNA-cleaving agents formed as conjugates of haloarenes and polyamides containing N-methylimidazole.	2004	15499657
Electrospray ionization mass spectrometric analysis of noncovalent complexes between DNA and polyamides containing N-methylpyrrole and N-methylimidazole.	2004	15216515
Electrospray ionization mass spectral fragmentation mechanisms of DNA-recognizing polyamides containing N-methylpyrrole and N-methylimidazol.	2004	15174197
[Synthesis and spectral properties of tailed sercine tetraphenylporphyrin cobalt complex].	2004 Apr	15766151
NTP technical report on the toxicity studies of 2- and 4-Methylimidazole (CAS No. 693-98-1 and 822-36-6) administered in feed to F344/N rats and B6C3F1 mice.	2004 Apr	15146214
Biology of N-methylpyrrole-N-methylimidazole hairpin polyamide.	2004 Apr	15056849
Phase I and pharmacokinetic study of irinotecan in combination with R115777, a farnesyl protein transferase inhibitor.	2004 Apr 19	15083177
Adenosylcobinamide plus exogenous, sterically hindered, putative axial bases: a reinvestigation into the cause of record levels of Co-C heterolysis.	2004 Apr 19	15074980
Formation and stability of N-heterocyclic carbenes in water: the carbon acid pKa of imidazolium cations in aqueous solution.	2004 Apr 7	15053626
Rapid biomonitoring of heterocyclic aromatic amines in human urine by tandem solvent solid phase extraction liquid chromatography electrospray ionization mass spectrometry.	2004 Aug	15310244
Toxicology and carcinogensis studies of 2-methylimidazole (Cas No. 693-98-1) in B6C3F1 mice (feed studies).	2004 Dec	15625556
Creatinine determination in serum by capillary electrophoresis.	2004 Feb	14760638
Energy dissipation processes of singlet-excited 1-hydroxyfluorenone and its hydrogen-bonded complex with N-methylimidazole.	2004 Jul-Aug	15339210
Study on reactions of 2-(dinitromethylene)-4,5-imidazolidinedione.	2004 Jun 25	15202891
Proximal and distal influences on ligand binding kinetics in microperoxidase and heme model compounds.	2004 Jun 8	15170339
Effect of methylimidazole-induced hypothyroidism in a model of low retinal neovascular incidence.	2004 Mar	14985311
(Salen)CrIIIX catalysts for the copolymerization of carbon dioxide and epoxides: role of the initiator and cocatalyst.	2004 Mar 22	15018499
Oligonucleotide-minor groove binder conjugates and their complexes with complementary DNA: effect of conjugate structural factors on the thermal stability of duplexes.	2004 May	15281367
Oligonucleotide--minor groove binder 1:2 conjugates: side by side parallel minor groove binder motif in stabilization of DNA duplex.	2004 Oct	15560087
Stereoselective tandem 1,4-addition reactions for benzenes: a comparison of Os(II), Re(I), and W(0) systems.	2004 Oct 27	15493934
Cross-species hybridisation of human and bovine orthologous genes on high density cDNA microarrays.	2004 Oct 28	15511299
Iron(III) complexes of sterically hindered tetradentate monophenolate ligands as functional models for catechol 1,2-dioxygenases: the role of ligand stereoelectronic properties.	2004 Oct 4	15446874
The first Cu(I)-mediated nucleophilic trifluoromethylation reactions using (trifluoromethyl)trimethylsilane in ionic liquids.	2004 Oct 7	15455143
Reactions of antimicrobial species to imidazole-microwave plasma reacted poly(dimethylsiloxane) surfaces.	2004 Sep 14	15350116
Cyclohexene oxide/CO2 copolymerization catalyzed by chromium(III) salen complexes and N-methylimidazole: effects of varying salen ligand substituents and relative cocatalyst loading.	2004 Sep 20	15360252
Colestilan, a new bile acid-sequestering resin, reduces bodyweight in postmenopausal women who have dieted unsuccessfully.	2005	16128597
[New therapy strategies in secondary hyperparathyroidism on dialysis (I): new concepts, new treatments].	2005	16050412
Synthesis and biological evaluation of 2',3'-didehydro-2',3'-dideoxy-9-deazaguanosine, a monophosphate prodrug and two analogues, 2',3'-dideoxy-9-deazaguanosine and 2',3'-didehydro-2',3'-dideoxy-9-deazainosine.	2005	15822619
Epididymal sperm granuloma induced by chronic administration of 2-methylimidazole in B6C3F1 mice.	2005	15814360
Copper(II) complexes of tridentate pyridylmethylethylenediamines: role of ligand steric hindrance on DNA binding and cleavage.	2005 Aug	16039720
Effect of MCI-196 (colestilan) as a phosphate binder on hyperphosphataemia in aemodialysis patients: a double-blind, placebo-controlled, short-term trial.	2005 Feb	15673691
[MnIII2 (5-Rsaltmen)2NiII(pao)2(L)]2+: an S(T)=3 building block for a single-chain magnet that behaves as a single-molecule magnet.	2005 Feb 18	15662681
Thermodynamic profiles for CO photodissociation from heme model compounds: effect of proximal ligands.	2005 Feb 21	15859280
Analysis of noncovalent complexes between human telomeric DNA and polyamides containing N-methylpyrrole and N-methylimidazole by using electrospray ionization mass spectrometry.	2005 Feb 4	15624127
From model compounds to protein binding: syntheses, characterizations and fluorescence studies of [RuII(bipy)(terpy)L]2+ complexes (bipy = 2,2'-bipyridine; terpy = 2,2':6',2''-terpyridine; L = imidazole, pyrazole and derivatives, cytochrome c).	2005 Jan 21	15616713
Charge donation to and dearomatization of benzene attending complexation: DFT estimates of binding energies of TpMXO(L) with benzene, for Tp = hydridotris(pyrazolyl) borate, MXO = MoNO, ReCO, and WNO, and L = ammonia, N-methylimidazole, pyridine, phosphine, methyl isocyanide, and carbon monoxide.	2005 Jan 30	15593348
Ligand orientation control in low-spin six-coordinate (porphinato)iron(II) species.	2005 Jun 13	15934765
Formation of a mutagenic heterocyclic aromatic amine from creatinine in urine of meat eaters and vegetarians.	2005 Mar	15777097
Electrospray negative ionization mass spectrometry of polyamides containing N-methylpyrrole and N-methylimidazole.	2005 May	15674858
Simple chip-based interfaces for on-line monitoring of supramolecular interactions by nano-ESI MS.	2005 Oct	16175268
Heme carbonyls: environmental effects on nu(C-O) and Fe-C/C-O bond length correlations.	2005 Oct 19	16218637
Catalytic conjugate additions of carbonyl anions under neutral aqueous conditions.	2005 Oct 26	16231921
Blue and near-UV phosphorescence from iridium complexes with cyclometalated pyrazolyl or N-heterocyclic carbene ligands.	2005 Oct 31	16241149
Dual catalyst control in the enantioselective intramolecular Morita-Baylis-Hillman reaction.	2005 Sep 1	16119914
NMR and theoretical study on the coordination and solution structures of the interaction between diperoxovanadate complexes and histidine-like ligands.	2005 Sep 19	16156634
Induction of thyroid lesions in 14-week toxicity studies of 2 and 4-methylimidazole in Fischer 344/N rats and B6C3F1 mice.	2006 Mar	16180012
Liquid chromatographic assay of ivermectin in human plasma for application to clinical pharmacokinetic studies.	2006 Mar 3	16242280

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:05:54 GMT 2023` Edited by `admin` on `Fri Dec 15 17:05:54 GMT 2023`
Record UNII	T0049Z45LZ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2-METHYLIMIDAZOLE

Systematic Name

English

EPIKURE-MI 2

Brand Name

English

2-METHYLIMIDAZOLE [IARC]

Common Name

English

METHYLIMIDAZOLE, 2-

Systematic Name

English

IMICURE-AMI 2

Brand Name

English

2-METHYL-1H-IMIDAZOLE

Systematic Name

English

ONDANSETRON HYDROCHLORIDE IMPURITY, 2-METHYLIMIDAZOLE- [USP IMPURITY]

Common Name

English

EPICURE-MI 2

Brand Name

English

1H-IMIDAZOLE, 2-METHYL-

Systematic Name

English

NSC-21394

Code

English

ONDANSETRON HYDROCHLORIDE DIHYDRATE IMPURITY F [EP IMPURITY]

Common Name

English

CUREZOL-2MZ-P

Brand Name

English

2-METHYLIMIDAZOLE [HSDB]

Common Name

English

Code System Code Type Description

FDA UNII

T0049Z45LZ