Zemocimig

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 17:02:25 GMT 2025` Edited by `admin` on `Wed Apr 02 17:02:25 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG4\|KAPPA\|LAMDA
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	SZN3M97G43
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

H-gamma4 heavy chain anti-F9a humanized (1-447) [VH (Homo sapiens IGHV3-23*04 (87.8%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.15] (26-33.51-58.97-111)) (1-122)-Homo sapiens IGHG4*01, nG4m(a) CH2 L92, 12-G4v5 h P10, 17-G4v57-1 CH1 K84.2, 18-G4v11 CH1 Q100

Preferred Name

English

Zemocimig

Official Name

English

zemocimig [INN]

Common Name

English

Immunoglobulin G4 [180-lysine,201-glutamine,230-proline,298-tyrosine,358-lysine,411-lysine,430-leucine,436-alanine,440-arginine,442-glutamic acid,447-proline,de-448-glycine,de-449-lysine], bispecific, anti-(human/Macaca fascicularis blood-coagulation fac

Common Name

English

immunoglobulin (H-gamma4_L-kappa)_( H-gamma4_L-lambda2), anti-[Homo sapiens F9a (coagulation factor F9, coagulation factor IX, hemophilia B) activated ] and anti-[Homo sapiens F10 (coagulation factor 10, coagulation factor X)], humanized and Homo sapiens

Common Name

English

Code System Code Type Description

INN

13346

Created by admin on Wed Apr 02 17:02:25 GMT 2025 , Edited by admin on Wed Apr 02 17:02:25 GMT 2025

PRIMARY

FDA UNII

SZN3M97G43

Created by admin on Wed Apr 02 17:02:25 GMT 2025 , Edited by admin on Wed Apr 02 17:02:25 GMT 2025

PRIMARY

CAS

2955620-21-8

Created by admin on Wed Apr 02 17:02:25 GMT 2025 , Edited by admin on Wed Apr 02 17:02:25 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_133	4_212
2_146	2_202
2_260	2_320
1_136	3_214
2_366	2_424
3_23	3_88
3_134	3_194
4_22	4_87
4_135	4_194
1_149	1_205
1_228	2_225
1_231	2_228
1_263	1_323
1_369	1_427

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_299
N	2_296

Related Record Type Details


					SZN3M97G43

Zemocimig

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS	Q		PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL