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Details

Stereochemistry ACHIRAL
Molecular Formula C17H19BrFNO2
Molecular Weight 368.2408
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 25B-NBF

SMILES

COc1cc(c(cc1CCNCc2ccccc2F)OC)Br

InChI

InChIKey=ATMBBMXJNIJRST-UHFFFAOYSA-N
InChI=1S/C17H19BrFNO2/c1-21-16-10-14(18)17(22-2)9-12(16)7-8-20-11-13-5-3-4-6-15(13)19/h3-6,9-10,20H,7-8,11H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C17H19BrFNO2
Molecular Weight 368.2408
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
8.57 null [pKi]
7.73 null [pKi]
PubMed

PubMed

TitleDatePubMed
In Vitro Metabolism of 25B-NBF, 2-(4-Bromo-2,5-Dimethoxyphenyl)-N-(2-Fluorobenzyl)ethanamine, in Human Hepatocytes Using Liquid Chromatography⁻Mass Spectrometry.
2019 Feb 25
Substance Class Chemical
Created
by admin
on Sat Jun 26 16:07:54 UTC 2021
Edited
by admin
on Sat Jun 26 16:07:54 UTC 2021
Record UNII
SSW3KY7SWW
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
25B-NBF
Common Name English
2C-B-NBF
Common Name English
2-(4-BROMO-2,5-DIMETHOXYPHENYL)-N-(2-FLUOROBENZYL)ETHAN-1-AMINE
Systematic Name English
25B-NBF [NFLIS-DRUG]
Common Name English
(2-(4-BROMO-2,5-DIMETHOXYPHENYL)ETHYL)((2-FLUOROPHENYL)METHYL)AMINE
Systematic Name English
BENZENEETHANAMINE, 4-BROMO-N-((2-FLUOROPHENYL)METHYL)-2,5-DIMETHOXY-
Systematic Name English
Code System Code Type Description
WIKIPEDIA
25B-NBF
Created by admin on Sat Jun 26 16:07:54 UTC 2021 , Edited by admin on Sat Jun 26 16:07:54 UTC 2021
PRIMARY
CAS
1391487-99-2
Created by admin on Sat Jun 26 16:07:54 UTC 2021 , Edited by admin on Sat Jun 26 16:07:54 UTC 2021
PRIMARY
FDA UNII
SSW3KY7SWW
Created by admin on Sat Jun 26 16:07:54 UTC 2021 , Edited by admin on Sat Jun 26 16:07:54 UTC 2021
PRIMARY
PUBCHEM
125181239
Created by admin on Sat Jun 26 16:07:54 UTC 2021 , Edited by admin on Sat Jun 26 16:07:54 UTC 2021
PRIMARY
MANUFACTURER PRODUCT INFORMATION
25B-NBF
Created by admin on Sat Jun 26 16:07:54 UTC 2021 , Edited by admin on Sat Jun 26 16:07:54 UTC 2021
PRIMARY 25B-NBF is an N-fluorobenzyl derivative of the phenethylamine hallucinogen 2C-B (Item No. 11734), which acts as a highly potent agonist for the 5-HT2C receptor. 25B-NBF binds human 5-HT2A receptors and rat 5-HT2C receptors with pKi values of 8.57 and 7.73, respectively.1 This product is intended for forensic and research applications.
Related Record Type Details
TARGET->PARTIAL AGONIST
Ki