25B-NBF

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NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C17H19BrFNO2
Molecular Weight	368.241
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 25B-NBF

Structure Search

SMILES

COC1=CC(CCNCC2=C(F)C=CC=C2)=C(OC)C=C1Br

InChI

InChIKey=ATMBBMXJNIJRST-UHFFFAOYSA-N

InChI=1S/C17H19BrFNO2/c1-21-16-10-14(18)17(22-2)9-12(16)7-8-20-11-13-5-3-4-6-15(13)19/h3-6,9-10,20H,7-8,11H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C17H19BrFNO2
Molecular Weight	368.241
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Serotonin 2a (5-HT2a) receptor 230 Target ID: CHEMBL224 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24397362	Agonist 2662		8.57 null [pKi]
Serotonin 2c (5-HT2c) receptor 122 Target ID: CHEMBL324 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24397362	Agonist 2662		7.73 null [pKi]

PubMed

PubMed

Title	Date	PubMed

Substance Class	Chemical Created by `admin` on `Thu Jul 06 15:48:26 UTC 2023` Edited by `admin` on `Thu Jul 06 15:48:26 UTC 2023`
Record UNII	SSW3KY7SWW
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

25B-NBF

Common Name

English

2C-B-NBF

Common Name

English

2-(4-BROMO-2,5-DIMETHOXYPHENYL)-N-(2-FLUOROBENZYL)ETHAN-1-AMINE

Systematic Name

English

25B-NBF [NFLIS-DRUG]

Common Name

English

(2-(4-BROMO-2,5-DIMETHOXYPHENYL)ETHYL)((2-FLUOROPHENYL)METHYL)AMINE

Systematic Name

English

BENZENEETHANAMINE, 4-BROMO-N-((2-FLUOROPHENYL)METHYL)-2,5-DIMETHOXY-

Systematic Name

English

Classification Tree Code System Code

WIKIPEDIA

Designer-drugs-25B-NBF

Created by admin on Thu Jul 06 15:48:26 UTC 2023 , Edited by admin on Thu Jul 06 15:48:26 UTC 2023

Code System Code Type Description

WIKIPEDIA

25B-NBF

Created by admin on Thu Jul 06 15:48:26 UTC 2023 , Edited by admin on Thu Jul 06 15:48:26 UTC 2023

PRIMARY

CAS

1391487-99-2

Created by admin on Thu Jul 06 15:48:26 UTC 2023 , Edited by admin on Thu Jul 06 15:48:26 UTC 2023

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EPA CompTox

DTXSID801337157

Created by admin on Thu Jul 06 15:48:26 UTC 2023 , Edited by admin on Thu Jul 06 15:48:26 UTC 2023

PRIMARY

FDA UNII

SSW3KY7SWW

Created by admin on Thu Jul 06 15:48:26 UTC 2023 , Edited by admin on Thu Jul 06 15:48:26 UTC 2023

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PUBCHEM

125181239

Created by admin on Thu Jul 06 15:48:26 UTC 2023 , Edited by admin on Thu Jul 06 15:48:26 UTC 2023

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MANUFACTURER PRODUCT INFORMATION

25B-NBF

Created by admin on Thu Jul 06 15:48:26 UTC 2023 , Edited by admin on Thu Jul 06 15:48:26 UTC 2023

PRIMARY

25B-NBF is an N-fluorobenzyl derivative of the phenethylamine hallucinogen 2C-B (Item No. 11734), which acts as a highly potent agonist for the 5-HT2C receptor. 25B-NBF binds human 5-HT2A receptors and rat 5-HT2C receptors with pKi values of 8.57 and 7.73, respectively.1 This product is intended for forensic and research applications.

Related Record Type Details


					NQI5D806LC

5-HYDROXYTRYPTAMINE RECEPTOR 2A

TARGET->PARTIAL AGONIST

Qualification:

Ki

Amount: