Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H8N2O2 |
| Molecular Weight | 140.1399 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1C(=O)NC=C(C)C1=O
InChI
InChIKey=IIDONYMEGWHGRU-UHFFFAOYSA-N
InChI=1S/C6H8N2O2/c1-4-3-7-6(10)8(2)5(4)9/h3H,1-2H3,(H,7,10)
| Molecular Formula | C6H8N2O2 |
| Molecular Weight | 140.1399 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase. | 2002 Sep 12 |
|
| Demethylation of 3-methylthymine in DNA by bacterial and human DNA dioxygenases. | 2004 Sep 24 |
|
| The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. | 2007 Nov 30 |
|
| Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO. | 2008 Oct 15 |
|
| 'Fat mass and obesity associated' gene (FTO): no significant association of variant rs9939609 with weight loss in a lifestyle intervention and lipid metabolism markers in German obese children and adolescents. | 2008 Sep 17 |
|
| A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene. | 2009 Aug |
|
| Formation and repair of tobacco carcinogen-derived bulky DNA adducts. | 2010 Dec 20 |
|
| Prevalence of loss-of-function FTO mutations in lean and obese individuals. | 2010 Jan |
|
| Structural and mutational analysis of Escherichia coli AlkB provides insight into substrate specificity and DNA damage searching. | 2010 Jan 13 |
|
| From monogenic to polygenic obesity: recent advances. | 2010 Mar |
|
| Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase. | 2010 Nov 11 |
|
| The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice. | 2010 Nov 16 |
|
| Mice lacking Alkbh1 display sex-ratio distortion and unilateral eye defects. | 2010 Nov 3 |
|
| Repair of DNA Alkylation Damage by the Escherichia coli Adaptive Response Protein AlkB as Studied by ESI-TOF Mass Spectrometry. | 2010 Oct 27 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 18:07:04 GMT 2023
by
admin
on
Fri Dec 15 18:07:04 GMT 2023
|
| Record UNII |
SS2K4WB6YL
|
| Record Status |
Validated (UNII)
|
| Record Version |
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SS2K4WB6YL
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