SODIUM TAUROGLYCOCHOLATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C28H47N2O8S.Na
Molecular Weight	594.736
Optical Activity	UNSPECIFIED
Defined Stereocenters	11 / 11
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)[C@H](C)CCC(=O)NCC(=O)NCCS([O-])(=O)=O

InChI

InChIKey=PUODKHBECQMSKY-QRPKJZHMSA-M

InChI=1S/C28H48N2O8S.Na/c1-16(4-7-24(34)30-15-25(35)29-10-11-39(36,37)38)19-5-6-20-26-21(14-23(33)28(19,20)3)27(2)9-8-18(31)12-17(27)13-22(26)32;/h16-23,26,31-33H,4-15H2,1-3H3,(H,29,35)(H,30,34)(H,36,37,38);/q;+1/p-1/t16-,17+,18-,19-,20+,21+,22-,23+,26+,27+,28-;/m1./s1

HIDE SMILES / InChI

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C28H47N2O8S
Molecular Weight	571.746
Charge	-1
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	10 / 11
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: http://www.epi4dogs.com/PDF%20Files/ENZAR%20FORTEdoc.pdf

Sodium tauroglycocholate presents in ENZAR FORTE tablet, together with enzymes: amylase, lipase and protease. ENZAR FORTE is indicated for the treatment of the following digestive symptoms: indigestion/dyspepsia; flatulence; bloating; fullness after eating; heartburn; anorexia; hepatic and pancreatic insufficiency; post-operative digestive upsets and convalescence. Discomfort, flatulence, and abdominal colic may result when the bodies own pancreatic enzymes cannot cope with excessive quantities of food consumed. In such cases, the enzymes present in ENZAR FORTE enhance the digestive processes in a natural way, thereby reducing the amount of undigested food available for fermentation & putrefaction. Amylase enzyme helps in the digestion of starch, lipase is involved in the digestion of lipids, and protease is required for digestion of proteins. The advantage of bile salt i.e. sodium tauroglycocholate for improving absorption of fat & fat-soluble vitamins.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Biliary acid transporting system 2 Target ID: Biliary acid transporting system Sources: https://www.ncbi.nlm.nih.gov/pubmed/8377117	Inhibitor 8297

Conditions

Condition	Modality	Highest Phase	Product
Indigestion/Dyspepsia 2 Sources: http://www.epi4dogs.com/PDF%20Files/ENZAR%20FORTEdoc.pdf	Palliative	Not Provided 504	ENZAR FORTE Approved Use Unknown
Pancreatitis 16 Sources: http://www.epi4dogs.com/PDF%20Files/ENZAR%20FORTEdoc.pdf	Palliative	Not Provided 504	ENZAR FORTE Approved Use Unknown
Flatulence 2 Sources: http://www.epi4dogs.com/PDF%20Files/ENZAR%20FORTEdoc.pdf	Palliative	Not Provided 504	ENZAR FORTE Approved Use Unknown
Heartburn 24 Sources: http://www.epi4dogs.com/PDF%20Files/ENZAR%20FORTEdoc.pdf	Palliative	Not Provided 504	ENZAR FORTE Approved Use Unknown
Anorexia 5 Sources: http://www.epi4dogs.com/PDF%20Files/ENZAR%20FORTEdoc.pdf	Palliative	Not Provided 504	ENZAR FORTE Approved Use Unknown
Hepatic and pancreatic insufficiency 2 Sources: http://www.epi4dogs.com/PDF%20Files/ENZAR%20FORTEdoc.pdf	Palliative	Not Provided 504	ENZAR FORTE Approved Use Unknown

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

As a digestive enzyme: 1 tablet to be sucked (not chewed) for few seconds and then swallowed with every meal. In pancreatic insufficiency: Up to 2 tablets 2-3 times a day can also be given. But dosage is individualized depending on patient’s pancreatic function.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:12:23 GMT 2023` Edited by `admin` on `Sat Dec 16 08:12:23 GMT 2023`
Record UNII	SR721549U5
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SODIUM TAUROGLYCOCHOLATE

Common Name

English

ETHANESULFONIC ACID, 2-((2-(((3.ALPHA.,5.BETA.,7.ALPHA.,12.ALPHA.)-3,7,12-TRIHYDROXY-24-OXOCHOLAN-24-YL)AMINO)ACETYL)AMINO)-, SODIUM SALT (1:1)

Systematic Name

English

ETHANESULFONIC ACID, 2-(((((3.ALPHA.,5.BETA.,7.ALPHA.,12.ALPHA.)-3,7,12-TRIHYDROXY-24-OXOCHOLAN-24-YL)AMINO)ACETYL)AMINO)-, MONOSODIUM SALT

Systematic Name

English

Sodium tauroglycocholate [WHO-DD]

Common Name

English

Code System Code Type Description

EVMPD

SUB15329MIG