Paltimatrectinib

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H15F5N6
Molecular Weight	434.3653
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

FC1=CC([C@H]2CCCN2C3=NC4=C(C=NN4C=C3)N5C=C(C=N5)C(F)(F)F)=C(F)C=C1

InChI

InChIKey=FYPXPQSPRRZJCK-MRXNPFEDSA-N

InChI=1S/C20H15F5N6/c21-13-3-4-15(22)14(8-13)16-2-1-6-29(16)18-5-7-30-19(28-18)17(10-27-30)31-11-12(9-26-31)20(23,24)25/h3-5,7-11,16H,1-2,6H2/t16-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C20H15F5N6
Molecular Weight	434.3653
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 18:57:03 GMT 2023` Edited by `admin` on `Sat Dec 16 18:57:03 GMT 2023`
Record UNII	SP4MKH8Y5J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Paltimatrectinib

Official Name

English

5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-3-[4-(trifluoromethyl)-1H-pyrazol-1-yl]pyrazolo[1,5-a]pyrimidine

Systematic Name

English

PBI-200

Code

English

PPI-5278

Code

English

paltimatrectinib [INN]

Common Name

English

PALTIMATRECTINIB [USAN]

Common Name

English

(R)-5-(2-(2,5-DIFLUOROPHENYL) PYRROLIDIN-1-YL)-3-(4-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL)PYRAZOLO(1,5-A) PYRIMIDINE

Systematic Name

English

Pyrazolo[1,5-a]pyrimidine, 5-[(2R)-2-(2,5-difluorophenyl)-1-pyrrolidinyl]-3-[4-(trifluoromethyl)-1H-pyrazol-1-yl]-

Systematic Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

827621