Details
Stereochemistry | ACHIRAL |
Molecular Formula | C6H8O2 |
Molecular Weight | 112.1265 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 1 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
C\C=C\C(=O)OC=C
InChI
InChIKey=IYNRVIKPUTZSOR-HWKANZROSA-N
InChI=1S/C6H8O2/c1-3-5-6(7)8-4-2/h3-5H,2H2,1H3/b5-3+
Molecular Formula | C6H8O2 |
Molecular Weight | 112.1265 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 1 |
Optical Activity | NONE |
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/5320882Curator's Comment: description was created based on several sources, including:
https://www.ncbi.nlm.nih.gov/pubmed/5334792 | https://www.ncbi.nlm.nih.gov/pubmed/13962902 | DOI: 10.1021/j100700a014
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5320882
Curator's Comment: description was created based on several sources, including:
https://www.ncbi.nlm.nih.gov/pubmed/5334792 | https://www.ncbi.nlm.nih.gov/pubmed/13962902 | DOI: 10.1021/j100700a014
Malethamer is the generic name of a new synthetic hydrocarbon copolymer with extraordinary water-binding properties, being able to absorb 200 times its weight of water. It is physically and chemically binds poliovirus 1 and certain bacterial enterotoxins. Ethylene-maleic anhydride copolymers and their derivatives have come to be considered for a number of applications generally involving the formation of insoluble complexes with proteins and viruses. The copolymer is not absorbed from the gastrointestinal tract and is pharmacologically inert. Malethamer, because of its water absorbing quality, is an effective compound for the symptomatic control of diarrhea, both organic and functional.
Originator
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5320882
Curator's Comment: # Eli Lilly
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5320882
500 mg after each bowel movement, but at least four times a day
Route of Administration:
Oral
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13962902
Ammoniated ethylene maleic anhydride copolymers and hydrolysed ethylene maleic anhydride copolymers of molecular weights approximating 120000 completely prevented cytopathogenicity at all Echo 9 virus concentrations (10-2 – 10-5).
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 05:14:40 GMT 2023
by
admin
on
Sat Dec 16 05:14:40 GMT 2023
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Record UNII |
SMC9A01NVS
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Record Status |
Validated (UNII)
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Record Version |
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3234-54-6
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238-930-6
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m3858
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SMC9A01NVS
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