U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 18:53:12 UTC 2021
Edited
by admin
on Sat Jun 26 18:53:12 UTC 2021
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
SM01RRU9KK
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BRII-198
Code English
Code System Code Type Description
FDA UNII
SM01RRU9KK
Created by admin on Sat Jun 26 18:53:13 UTC 2021 , Edited by admin on Sat Jun 26 18:53:13 UTC 2021
PRIMARY
From To
1_22 1_96
2_22 2_96
2_146 2_202
2_222 4_213
2_263 2_323
1_146 1_202
2_369 2_427
3_22 3_87
3_136 3_195
4_22 4_87
4_136 4_195
1_222 3_213
1_228 2_228
1_231 2_231
1_263 1_323
1_369 1_427
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_299
N 2_299
Related Record Type Details
TARGET -> INHIBITOR
BRII-198 has no or moderately reduced binding activity (approximately two to three-fold) to human Fc? receptors (Fc?R I, Fc?R IIa, Fc?R IIb, Fc?R IIIa.
BINDING
TARGET ORGANISM->INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL