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Details

Stereochemistry ACHIRAL
Molecular Formula C8H12N4.2ClH
Molecular Weight 237.13
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1-(2-PYRIMIDINYL)PIPERAZINE DIHYDROCHLORIDE

SMILES

Cl.Cl.C1CN(CCN1)C2=NC=CC=N2

InChI

InChIKey=ZNZGJSLHXOMREP-UHFFFAOYSA-N
InChI=1S/C8H12N4.2ClH/c1-2-10-8(11-3-1)12-6-4-9-5-7-12;;/h1-3,9H,4-7H2;2*1H

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C8H12N4
Molecular Weight 164.2077
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
Human cytochromes mediating gepirone biotransformation at low substrate concentrations.
2003 Mar
Pharmacokinetic evaluation of gepirone immediate-release capsules and gepirone extended-release tablets in healthy volunteers.
2003 Sep
Oral buspirone causes a shift in the dose-response curve between the elevated-plus maze and Vogel conflict tests in Long-Evans rats: relation of brain levels of buspirone and 1-PP to anxiolytic action.
2005 May
Pharmacokinetics of buspirone in autistic children.
2006 May
Mass spectrometry analysis of phosphopeptides after peptide carboxy group derivatization.
2008 Nov 1
Pharmacokinetic interaction between tandospirone and fluvoxamine in the rat contextual conditioned fear stress model and its functional consequence: Involvement of cytochrome P450 3A4.
2008 Oct
Patents

Patents

04845221
2
04895848
2
04935424
2
04988814
2
05021569
2
05141930
2
05162322
8
05258379
4
05428038
2
05565456
2
05594141
3
05677454
3
05688791
2
05852019
4
05912246
7
05912350
3
06013654
4
06172061
2
06221871
3
06281359
3
06335324
2
06455528
10
06555541
3
06673800
4
06936607
2
07253165
6
07601856
3
07888352
3
08022205
19
08053457
6
08153629
4
08252792
4
08263633
6
08269002
4
08314100
7
08466150
2
08598173
7
08722883
3
JP2002542287A
30
Substance Class Chemical
Created
by admin
on Wed Apr 02 19:23:13 GMT 2025
Edited
by admin
on Wed Apr 02 19:23:13 GMT 2025
Record UNII
SLC2P2PLG8
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
1-(2-PYRIMIDINYL)PIPERAZINE DIHYDROCHLORIDE
Common Name English
2-PIPERAZINYLPYRIMIDINE DIHYDROCHLORIDE
Preferred Name English
1-PP dihydrochloride
Common Name English
Code System Code Type Description
CAS
94021-22-4
Created by admin on Wed Apr 02 19:23:13 GMT 2025 , Edited by admin on Wed Apr 02 19:23:13 GMT 2025
PRIMARY
PUBCHEM
11680272
Created by admin on Wed Apr 02 19:23:13 GMT 2025 , Edited by admin on Wed Apr 02 19:23:13 GMT 2025
PRIMARY
ECHA (EC/EINECS)
301-415-2
Created by admin on Wed Apr 02 19:23:13 GMT 2025 , Edited by admin on Wed Apr 02 19:23:13 GMT 2025
PRIMARY
FDA UNII
SLC2P2PLG8
Created by admin on Wed Apr 02 19:23:13 GMT 2025 , Edited by admin on Wed Apr 02 19:23:13 GMT 2025
PRIMARY
EPA CompTox
DTXSID70240234
Created by admin on Wed Apr 02 19:23:13 GMT 2025 , Edited by admin on Wed Apr 02 19:23:13 GMT 2025
PRIMARY
Related Record Type Details
Structure of 1-(2-PYRIMIDINYL)PIPERAZINE
PARENT -> SALT/SOLVATE
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