(?R)-?-2-Pyridinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C17H10F6N2O
Molecular Weight	372.2645
Optical Activity	( - )
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of (?R)-?-2-Pyridinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol

Structure Search

SMILES

O[C@@H](C1=NC=CC=C1)C2=C3C=CC=C(C3=NC(=C2)C(F)(F)F)C(F)(F)F

InChI

InChIKey=LUDFDSXDVJABBT-OAHLLOKOSA-N

InChI=1S/C17H10F6N2O/c18-16(19,20)11-5-3-4-9-10(15(26)12-6-1-2-7-24-12)8-13(17(21,22)23)25-14(9)11/h1-8,15,26H/t15-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C17H10F6N2O
Molecular Weight	372.2645
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Mon Mar 31 23:23:24 GMT 2025` Edited by `admin` on `Mon Mar 31 23:23:24 GMT 2025`
Record UNII	SK3SSY8HE0
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

(?R)-?-2-Pyridinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol

Systematic Name

English

MEFLOQUINE HYDROCHLORIDE IMPURITY C [WHO-IP]

Preferred Name

English

RAC-(R)-(2,8-BIS(TRIFLUOROMETHYL)QUINOLIN-4-YL)(PYRIDIN-2-YL)METHANOL

Systematic Name

English

4-QUINOLINEMETHANOL, .ALPHA.-2-PYRIDINYL-2,8-BIS(TRIFLUOROMETHYL)-, (R)-

Systematic Name

English

4-QUINOLINEMETHANOL, .ALPHA.-2-PYRIDINYL-2,8-BIS(TRIFLUOROMETHYL)-, (.ALPHA.R)-

Systematic Name

English

Code System Code Type Description

FDA UNII

SK3SSY8HE0

Created by admin on Mon Mar 31 23:23:25 GMT 2025 , Edited by admin on Mon Mar 31 23:23:25 GMT 2025

PRIMARY

PUBCHEM

11257265

Created by admin on Mon Mar 31 23:23:25 GMT 2025 , Edited by admin on Mon Mar 31 23:23:25 GMT 2025

PRIMARY

CAS

151592-79-9

Created by admin on Mon Mar 31 23:23:25 GMT 2025 , Edited by admin on Mon Mar 31 23:23:25 GMT 2025

PRIMARY

Related Record Type Details


					LR2SRP2P6J

?-2-Pyridinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol

RACEMATE -> ENANTIOMER

Amount:

Related Record Type Details


					5Y9L3636O3

MEFLOQUINE HYDROCHLORIDE

PARENT -> IMPURITY

Comments:

In the chromatogram obtained with solution (1) the following impurities, if present, are eluted at the following relative retention with reference to mefloquine (retention time about 3.9 minutes): impurity C about 3.6. In the chromatogram obtained with solution (1):the area of any other peak, apart from the principal peak, is not greater than 0.5 times the area of the peak in the chromatogram obtained with solution (2) (0.1%).

Amount: