U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Tue Apr 01 16:45:20 GMT 2025
Edited
by admin
on Tue Apr 01 16:45:20 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
SK1LVT23A1
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ELEZANUMAB
INN  
INN  
Official Name English
elezanumab [INN]
Preferred Name English
ABT-555
Code English
IMMUNOGLOBULIN, ANTI-(REPULSIVE GUIDANCE MOLECULE RGMA) (HUMAN MONOCLONAL PR-1432051 HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL PR-1432051 LIGHT CHAIN, DIMER
Systematic Name English
Elezanumab [WHO-DD]
Common Name English
AE12-1Y-QL
Code English
IMMUNOGLOBULIN G1-LAMBDA1, ANTI-(HOMO SAPIENS RGMA (REPULSIVE GUIDANCE MOLECULE FAMILY MEMBER A, REPULSIVE GUIDANCE MOLECULE A, RGMA)), HOMO SAPIENS MONOCLONAL ANTIBODY
Systematic Name English
IMMUNOGLOBULIN G1-LAMBDA 1, ANTI-(HOMO SAPIENS REPULSIVE GUIDANCE MOLECULE A)HOMO SAPIENS MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-450) (HOMO SAPIENS VH (IGHV1-18*01 (93%) (IGHD)-IGHJ3*01 (92%)) (8.8.13) (1-120)-HOMO SAPIENS IGHG1*01(CH2(L4>A(237),L5>A
Systematic Name English
ELEZANUMAB [USAN]
Common Name English
PR-1432051
Code English
Classification Tree Code System Code
FDA ORPHAN DRUG 729419
Created by admin on Tue Apr 01 16:45:20 GMT 2025 , Edited by admin on Tue Apr 01 16:45:20 GMT 2025
Code System Code Type Description
INN
10344
Created by admin on Tue Apr 01 16:45:20 GMT 2025 , Edited by admin on Tue Apr 01 16:45:20 GMT 2025
PRIMARY
CAS
1791416-49-3
Created by admin on Tue Apr 01 16:45:20 GMT 2025 , Edited by admin on Tue Apr 01 16:45:20 GMT 2025
PRIMARY
NCI_THESAURUS
C169936
Created by admin on Tue Apr 01 16:45:20 GMT 2025 , Edited by admin on Tue Apr 01 16:45:20 GMT 2025
PRIMARY
FDA UNII
SK1LVT23A1
Created by admin on Tue Apr 01 16:45:20 GMT 2025 , Edited by admin on Tue Apr 01 16:45:20 GMT 2025
PRIMARY
USAN
FG-10
Created by admin on Tue Apr 01 16:45:20 GMT 2025 , Edited by admin on Tue Apr 01 16:45:20 GMT 2025
PRIMARY
DRUG BANK
DB15240
Created by admin on Tue Apr 01 16:45:20 GMT 2025 , Edited by admin on Tue Apr 01 16:45:20 GMT 2025
PRIMARY
SMS_ID
100000174553
Created by admin on Tue Apr 01 16:45:20 GMT 2025 , Edited by admin on Tue Apr 01 16:45:20 GMT 2025
PRIMARY
From To
1_22 1_96
1_147 1_203
1_264 1_324
1_370 1_428
2_22 2_96
2_147 2_203
2_264 2_324
2_370 2_428
3_22 3_90
3_137 3_196
4_22 4_90
4_137 4_196
1_223 3_214
2_223 4_214
1_229 2_229
1_232 2_232
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_300
N 2_300
Related Record Type Details
REPULSIVE GUIDANCE MOLECULE A
TARGET -> INHIBITOR
Related Record Type Details
ELEZANUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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