PD-98059

COC1=C(N)C(=CC=C1)C2=CC(=O)C3=C(O2)C=CC=C3

InChIKey=QFWCYNPOPKQOKV-UHFFFAOYSA-N

InChI=1S/C16H13NO3/c1-19-14-8-4-6-11(16(14)17)15-9-12(18)10-5-2-3-7-13(10)20-15/h2-9H,17H2,1H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
Dual specificity mitogen-activated protein kinase kinase 1 20 Target ID: CHEMBL3587 Sources: https://www.ncbi.nlm.nih.gov/pubmed/12672248 \| https://www.ncbi.nlm.nih.gov/pubmed/7499206	Inhibitor 8504		2.0 µM [IC50]
Serine/threonine-protein kinase RAF and Dual specificity mitogen-activated protein kinase kinase 1 (Raf/MEK) 1 Target ID: CHEMBL2111351 Sources: https://www.ncbi.nlm.nih.gov/pubmed/11784156	Inhibitor 8504		2.8 µM [IC50]

Substance Class	Chemical Created by `admin` on `Mon Mar 31 23:37:10 GMT 2025` Edited by `admin` on `Mon Mar 31 23:37:10 GMT 2025`
Record UNII	SJE1IO5E3I
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

NSC-679829

Preferred Name

English

PD-98059

Code

English

2-(2'-AMINO-3'-METHOXYPHENYL)OXANAPHTHALEN-4-ONE

Systematic Name

English

4H-1-BENZOPYRAN-4-ONE, 2-(2-AMINO-3-METHOXYPHENYL)-

Systematic Name

English

2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE

Systematic Name

English

PD-098059

Code

English

PD 98059 [WHO-DD]

Common Name

English

NSC-679828

Code

English

Code System Code Type Description

FDA UNII

SJE1IO5E3I