TRELNARIZINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C28H30F2N2O2
Molecular Weight	464.5468
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC=C(\C=C\CN2CCN(CC2)C(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)C=C1OC

InChI

InChIKey=CELDOXOGIZIYPY-ONEGZZNKSA-N

InChI=1S/C28H30F2N2O2/c1-33-26-14-5-21(20-27(26)34-2)4-3-15-31-16-18-32(19-17-31)28(22-6-10-24(29)11-7-22)23-8-12-25(30)13-9-23/h3-14,20,28H,15-19H2,1-2H3/b4-3+

HIDE SMILES / InChI

Molecular Formula	C28H30F2N2O2
Molecular Weight	464.5468
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2625466 | https://apps.who.int/iris/bitstream/handle/10665/67830/WHO_EDM_QSM_2003.2.pdf

Trelnarizine is a new difluorinated piperazine derivative with a structural resemblance to flunarizine and cinnarizine and possessing calcium antagonist activity. Trelnarizine belongs to the antihistaminic, vasodilator agents.

Approval Year

PubMed

Title	Date	PubMed
Assay of a calcium antagonist (PU 122) in plasma by gas chromatography.	1989 Dec 29	2625466

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:51:32 GMT 2023` Edited by `admin` on `Fri Dec 15 15:51:32 GMT 2023`
Record UNII	SE8X571K4C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TRELNARIZINE

Official Name

English

trelnarizine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29707