6-BROMO-(2-CHLOROPHENYL) QUINAZOLINE-2-ONE

ClC1=CC=CC(Br)=C1C2=NC(=O)NC3=C2C=CC=C3

InChIKey=NPBVBQPOVFGISZ-UHFFFAOYSA-N

InChI=1S/C14H8BrClN2O/c15-9-5-3-6-10(16)12(9)13-8-4-1-2-7-11(8)17-14(19)18-13/h1-7H,(H,17,18,19)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
NF-kappa B signaling pathway 87 Target ID: map04064 Sources: https://www.ncbi.nlm.nih.gov/pubmed/12517433	Inhibitor 8504		11.0 nM [IC50]
store-operated calcium entry 4 Target ID: GO:0002115 Sources: https://www.ncbi.nlm.nih.gov/pubmed/21700213	Inhibitor 8504

Substance Class	Chemical Created by `admin` on `Wed Apr 02 11:06:14 GMT 2025` Edited by `admin` on `Wed Apr 02 11:06:14 GMT 2025`
Record UNII	SDR4PJJ2KD
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

QNZ

Preferred Name

English

6-BROMO-(2-CHLOROPHENYL) QUINAZOLINE-2-ONE

Systematic Name

English

Code System Code Type Description

FDA UNII

SDR4PJJ2KD

Created by admin on Wed Apr 02 11:06:14 GMT 2025 , Edited by admin on Wed Apr 02 11:06:14 GMT 2025

PRIMARY

PUBCHEM

91179092

Created by admin on Wed Apr 02 11:06:14 GMT 2025 , Edited by admin on Wed Apr 02 11:06:14 GMT 2025

PRIMARY

Related Record Type Details


					3DSB43090Z

PARENT -> METABOLITE

Qualification:

PLASMA; URINE

Amount: