Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C9H18N2OS |
| Molecular Weight | 202.317 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC[C@H](C)[C@H](N)C(=O)N1CCSC1
InChI
InChIKey=WCRLBFHWFPELKW-YUMQZZPRSA-N
InChI=1S/C9H18N2OS/c1-3-7(2)8(10)9(12)11-4-5-13-6-11/h7-8H,3-6,10H2,1-2H3/t7-,8-/m0/s1
| Molecular Formula | C9H18N2OS |
| Molecular Weight | 202.317 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Improved glucose tolerance in Zucker fatty rats by oral administration of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide. | 1998 Aug |
|
| Long-term treatment with dipeptidyl peptidase IV inhibitor improves hepatic and peripheral insulin sensitivity in the VDF Zucker rat: a euglycemic-hyperinsulinemic clamp study. | 2002 Sep |
|
| Improvement of glucose tolerance in Zucker diabetic fatty rats by long-term treatment with the dipeptidyl peptidase inhibitor P32/98: comparison with and combination with rosiglitazone. | 2005 Mar |
|
| 8-(3-(R)-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a highly potent, selective, long-acting, and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes. | 2007 Dec 27 |
|
| Inhibition of dipeptidyl peptidase IV (DPP IV) is one of the mechanisms explaining the hypoglycemic effect of berberine. | 2009 Oct |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 14:08:36 UTC 2023
by
admin
on
Sat Dec 16 14:08:36 UTC 2023
|
| Record UNII |
SDH8E9EM4L
|
| Record Status |
Validated (UNII)
|
| Record Version |
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-
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DTXSID00849592
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6918465
Created by
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136259-20-6
Created by
admin on Sat Dec 16 14:08:36 UTC 2023 , Edited by admin on Sat Dec 16 14:08:36 UTC 2023
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SDH8E9EM4L
Created by
admin on Sat Dec 16 14:08:36 UTC 2023 , Edited by admin on Sat Dec 16 14:08:36 UTC 2023
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| Related Record | Type | Details | ||
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TARGET -> INHIBITOR |
