U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
Elsiglutide (ZP 1846) is a synthetic 39-amino acid glucagon-like peptide-2 (GLP-2) analogue. Upon subcutaneous administration, elsiglutide binds to GLP-2 receptors and thereby promotes proliferation of epithelial cells. Elsiglutide prevents or reduces the occurrence of gastrointestinal damage caused by chemotherapeutic agents, including gastrointestinal mucositis and chemotherapy-induced diarrhea (CID). Elsiglutide is being developed by Helsinn Healthcare, for the prevention of chemotherapy-induced diarrhoea.

Approval Year

Patents

Patents

Substance Class Protein
Created
by admin
on Sat Dec 16 14:55:18 GMT 2023
Edited
by admin
on Sat Dec 16 14:55:18 GMT 2023
Protein Sub Type
Record UNII
SC864Q40VB
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ELSIGLUTIDE
INN   WHO-DD  
INN  
Official Name English
ZP1846
Code English
L-LYSINAMIDE, L-HISTIDYLGLYCYL-L-.ALPHA.-GLUTAMYLGLYCYL-L-SERYL-L-PHENYLALANYL-L-SERYL-L-SERYL-L-.ALPHA.-GLUTAMYL-L-LEUCYL-L-SERYL-L-THREONYL-L-ISOLEUCYL-L-LEUCYL-L-.ALPHA.-ASPARTYL-L-ALANYL-L-LEUCYL-L-ALANYL-L-ALANYL-L-ARGINYL-L-.ALPHA.-ASPARTYL-L-PHENY
Systematic Name English
Elsiglutide [WHO-DD]
Common Name English
ZP-1846
Code English
elsiglutide [INN]
Common Name English
HIS-GLY-GLU-GLY-THR-PHE-SER-SER-GLU-LEU-SER-THR-ILE-LEU-ASP-ALA-LEU-ALA-ALA-ARG-ASP-PHE-ILE-ALA-TRP-LEU-ILE-ALA-THR-LYS-ILE-THR-ASP-LYS-LYS-LYS-LYS-LYS-LYS-NH2
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C266
Created by admin on Sat Dec 16 14:55:18 GMT 2023 , Edited by admin on Sat Dec 16 14:55:18 GMT 2023
Code System Code Type Description
CAS
914009-84-0
Created by admin on Sat Dec 16 14:55:18 GMT 2023 , Edited by admin on Sat Dec 16 14:55:18 GMT 2023
PRIMARY
FDA UNII
SC864Q40VB
Created by admin on Sat Dec 16 14:55:18 GMT 2023 , Edited by admin on Sat Dec 16 14:55:18 GMT 2023
PRIMARY
INN
9407
Created by admin on Sat Dec 16 14:55:18 GMT 2023 , Edited by admin on Sat Dec 16 14:55:18 GMT 2023
PRIMARY
ChEMBL
CHEMBL2108318
Created by admin on Sat Dec 16 14:55:18 GMT 2023 , Edited by admin on Sat Dec 16 14:55:18 GMT 2023
PRIMARY
DRUG BANK
DB06336
Created by admin on Sat Dec 16 14:55:18 GMT 2023 , Edited by admin on Sat Dec 16 14:55:18 GMT 2023
PRIMARY
NCI_THESAURUS
C101131
Created by admin on Sat Dec 16 14:55:18 GMT 2023 , Edited by admin on Sat Dec 16 14:55:18 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL