Elsiglutide (ZP 1846) is a synthetic 39-amino acid glucagon-like peptide-2 (GLP-2) analogue. Upon subcutaneous administration, elsiglutide binds to GLP-2 receptors and thereby promotes proliferation of epithelial cells. Elsiglutide prevents or reduces the occurrence of gastrointestinal damage caused by chemotherapeutic agents, including gastrointestinal mucositis and chemotherapy-induced diarrhea (CID). Elsiglutide is being developed by Helsinn Healthcare, for the prevention of chemotherapy-induced diarrhoea.
Originator
Approval Year
Substance Class |
Protein
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admin
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Edited
Sat Dec 16 14:55:18 GMT 2023
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admin
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Sat Dec 16 14:55:18 GMT 2023
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Protein Sub Type | |
Record UNII |
SC864Q40VB
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Record Status |
Validated (UNII)
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NCI_THESAURUS |
C266
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Code System | Code | Type | Description | ||
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914009-84-0
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SC864Q40VB
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admin on Sat Dec 16 14:55:18 GMT 2023 , Edited by admin on Sat Dec 16 14:55:18 GMT 2023
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9407
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CHEMBL2108318
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DB06336
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C101131
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admin on Sat Dec 16 14:55:18 GMT 2023 , Edited by admin on Sat Dec 16 14:55:18 GMT 2023
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Related Record | Type | Details | ||
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ACTIVE MOIETY |
Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
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MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
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Molecular Formula | CHEMICAL |
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