Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | 2C19H29N2O5S.Ca |
| Molecular Weight | 835.096 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 6 / 6 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Ca++].C[C@H](CSC(=O)[C@@H](C)NC(=O)C1CCCCC1)C(=O)N2CCC[C@H]2C([O-])=O.C[C@H](CSC(=O)[C@@H](C)NC(=O)C3CCCCC3)C(=O)N4CCC[C@H]4C([O-])=O
InChI
InChIKey=CUZMQPZYCDIHQL-VCTVXEGHSA-L
InChI=1S/2C19H30N2O5S.Ca/c2*1-12(17(23)21-10-6-9-15(21)18(24)25)11-27-19(26)13(2)20-16(22)14-7-4-3-5-8-14;/h2*12-15H,3-11H2,1-2H3,(H,20,22)(H,24,25);/q;;+2/p-2/t2*12-,13-,15+;/m11./s1
| Molecular Formula | Ca |
| Molecular Weight | 40.078 |
| Charge | 2 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C19H29N2O5S |
| Molecular Weight | 397.509 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Moveltipril is a captopril derivative patented by Japanese pharmaceutical company Chugai Pharmaceutical Co., Ltd. as an angiotensin-converting enzyme inhibitor, that decreases systemic blood pressure more slowly and persistently than captopril. Moveltipril is partially metabolized to captopril by hydrolysis, predominantly in the liver. In preclinical studies administration of Moveltipril to the anesthetized dogs produced a gradual and dose-dependent decline in aortic pressure associated with no marked changes in coronary blood flow, heart rate. Both Moveltipril and captopril inhibited selectively the pressor response to angiotensin I in a dose-related manner.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 20:06:49 GMT 2025
by
admin
on
Mon Mar 31 20:06:49 GMT 2025
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| Record UNII |
SB44S25HE5
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| Record Status |
Validated (UNII)
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| Record Version |
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6917881
Created by
admin on Mon Mar 31 20:06:49 GMT 2025 , Edited by admin on Mon Mar 31 20:06:49 GMT 2025
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PRIMARY | |||
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SB44S25HE5
Created by
admin on Mon Mar 31 20:06:49 GMT 2025 , Edited by admin on Mon Mar 31 20:06:49 GMT 2025
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PRIMARY | |||
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85921-53-5
Created by
admin on Mon Mar 31 20:06:49 GMT 2025 , Edited by admin on Mon Mar 31 20:06:49 GMT 2025
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m7641
Created by
admin on Mon Mar 31 20:06:49 GMT 2025 , Edited by admin on Mon Mar 31 20:06:49 GMT 2025
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PRIMARY | Merck Index |
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PARENT -> SALT/SOLVATE |
