Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | 2C19H29N2O5S.Ca |
| Molecular Weight | 835.096 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 6 / 6 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Ca++].C[C@H](CSC(=O)[C@@H](C)NC(=O)C1CCCCC1)C(=O)N2CCC[C@H]2C([O-])=O.C[C@H](CSC(=O)[C@@H](C)NC(=O)C3CCCCC3)C(=O)N4CCC[C@H]4C([O-])=O
InChI
InChIKey=CUZMQPZYCDIHQL-VCTVXEGHSA-L
InChI=1S/2C19H30N2O5S.Ca/c2*1-12(17(23)21-10-6-9-15(21)18(24)25)11-27-19(26)13(2)20-16(22)14-7-4-3-5-8-14;/h2*12-15H,3-11H2,1-2H3,(H,20,22)(H,24,25);/q;;+2/p-2/t2*12-,13-,15+;/m11./s1
| Molecular Formula | Ca |
| Molecular Weight | 40.078 |
| Charge | 2 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C19H29N2O5S |
| Molecular Weight | 397.509 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Moveltipril is a captopril derivative patented by Japanese pharmaceutical company Chugai Pharmaceutical Co., Ltd. as an angiotensin-converting enzyme inhibitor, that decreases systemic blood pressure more slowly and persistently than captopril. Moveltipril is partially metabolized to captopril by hydrolysis, predominantly in the liver. In preclinical studies administration of Moveltipril to the anesthetized dogs produced a gradual and dose-dependent decline in aortic pressure associated with no marked changes in coronary blood flow, heart rate. Both Moveltipril and captopril inhibited selectively the pressor response to angiotensin I in a dose-related manner.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 20:17:55 GMT 2023
by
admin
on
Fri Dec 15 20:17:55 GMT 2023
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| Record UNII |
SB44S25HE5
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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6917881
Created by
admin on Fri Dec 15 20:17:55 GMT 2023 , Edited by admin on Fri Dec 15 20:17:55 GMT 2023
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SB44S25HE5
Created by
admin on Fri Dec 15 20:17:55 GMT 2023 , Edited by admin on Fri Dec 15 20:17:55 GMT 2023
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85921-53-5
Created by
admin on Fri Dec 15 20:17:55 GMT 2023 , Edited by admin on Fri Dec 15 20:17:55 GMT 2023
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m7641
Created by
admin on Fri Dec 15 20:17:55 GMT 2023 , Edited by admin on Fri Dec 15 20:17:55 GMT 2023
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PRIMARY | Merck Index |
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PARENT -> SALT/SOLVATE |
