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Details

Stereochemistry ABSOLUTE
Molecular Formula C24H36O5
Molecular Weight 404.5406
Optical Activity UNSPECIFIED
Defined Stereocenters 8 / 8
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of EPILOVASTATIN

SMILES

CC[C@@]([H])(C)C(=O)O[C@@]1([H])C[C@@]([H])(C)C=C2C=C[C@]([H])(C)[C@]([H])(CC[C@]3([H])C[C@]([H])(CC(=O)O3)O)[C@]21[H]

InChI

InChIKey=PCZOHLXUXFIOCF-YPQFMRJXSA-N
InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15+,16-,18+,19+,20-,21-,23-/m0/s1

HIDE SMILES / InChI

Molecular Formula C24H36O5
Molecular Weight 404.5406
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 8 / 8
E/Z Centers 0
Optical Activity UNSPECIFIED

Epilovastatin is a Lovastatin impurity (Simvastatin Impurity F).

Approval Year

Substance Class Chemical
Created
by admin
on Sat Jun 26 06:02:58 UTC 2021
Edited
by admin
on Sat Jun 26 06:02:58 UTC 2021
Record UNII
S9XFL13C1F
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
EPILOVASTATIN
Common Name English
SIMVASTATIN SPECIFIED IMPURITY F [EP]
Common Name English
BUTANOIC ACID, 2-METHYL-, (1S,3R,7S,8S,8AR)-1,2,3,7,8,8A-HEXAHYDRO-3,7-DIMETHYL-8-(2-((2R,4R)-TETRAHYDRO-4-HYDROXY-6-OXO-2H-PYRAN-2-YL)ETHYL)-1-NAPHTHALENYL ESTER, (2R)-
Systematic Name English
SIMVASTATIN IMPURITY, EPILOVASTATIN- [USP]
Common Name English
(1S,3R,7S,8S,8AR)-8-(2-((2R,4R)-4-HYDROXY-6-OXOTETRAHYDRO-2H-PYRAN-2-YL)ETHYL)-3,7-DIMETHYL-1,2,3,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL (2R)-2-METHYLBUTANOATE
Systematic Name English
Code System Code Type Description
PUBCHEM
40785065
Created by admin on Sat Jun 26 06:02:58 UTC 2021 , Edited by admin on Sat Jun 26 06:02:58 UTC 2021
PRIMARY
FDA UNII
S9XFL13C1F
Created by admin on Sat Jun 26 06:02:58 UTC 2021 , Edited by admin on Sat Jun 26 06:02:58 UTC 2021
PRIMARY
CAS
79952-44-6
Created by admin on Sat Jun 26 06:02:58 UTC 2021 , Edited by admin on Sat Jun 26 06:02:58 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> IMPURITY
sum of impurities E and F: not more than twice the area of the principal peak in the chromatogram obtained with reference solution (b) (1.0 per cent)
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP