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Details

Stereochemistry ACHIRAL
Molecular Formula C36H36N2O3.ClH
Molecular Weight 581.144
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FETOXYLATE HYDROCHLORIDE

SMILES

Cl.O=C(OCCOC1=CC=CC=C1)C2(CCN(CCC(C#N)(C3=CC=CC=C3)C4=CC=CC=C4)CC2)C5=CC=CC=C5

InChI

InChIKey=DHAXFWAIZHJURV-UHFFFAOYSA-N
InChI=1S/C36H36N2O3.ClH/c37-29-36(31-15-7-2-8-16-31,32-17-9-3-10-18-32)23-26-38-24-21-35(22-25-38,30-13-5-1-6-14-30)34(39)41-28-27-40-33-19-11-4-12-20-33;/h1-20H,21-28H2;1H

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C36H36N2O3
Molecular Weight 544.6826
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

FETOXYLATE, a phenoxyethyl ester of diphenoxylate, is an opioid receptor agonist. It is used as antidiarrheal.

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
Loperamide: blockade of calcium channels as a mechanism for antidiarrheal effects.
1984 Dec

Sample Use Guides

In Vitro Use Guide
The antidiarrheal opiates loperamide, fluperamide, diphenoxylate, and fetoxylate inhibited binding of [3H]nitrendipine to membranes from guinea-pig cerebral cortex with Ki values of 0.5 to 10 microM.
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:05:20 UTC 2023
Edited
by admin
on Fri Dec 15 15:05:20 UTC 2023
Record UNII
S9P9G7VI54
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FETOXYLATE HYDROCHLORIDE
USAN  
USAN  
Official Name English
R 13,558
Code English
FETOXYLATE HYDROCHLORIDE [USAN]
Common Name English
MCN-JR-13558-11
Code English
FETOXYLATE HCL
Common Name English
4-PIPERIDINECARBOXYLIC ACID, 1-(3-CYANO-3,3-DIPHENYLPROPYL)-4-PHENYL-, 2-PHENOXYETHYL ESTER, MONOHYDROCHLORIDE
Common Name English
MCN-JR-13,558-11
Code English
R-13558
Code English
Fetoxilate hydrochloride [WHO-DD]
Common Name English
FETOXILATE HYDROCHLORIDE
WHO-DD  
Common Name English
2-Phenoxyethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotate monohydrochloride
Systematic Name English
FETOXILATE HCL
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29696
Created by admin on Fri Dec 15 15:05:20 UTC 2023 , Edited by admin on Fri Dec 15 15:05:20 UTC 2023
Code System Code Type Description
PUBCHEM
32026
Created by admin on Fri Dec 15 15:05:20 UTC 2023 , Edited by admin on Fri Dec 15 15:05:20 UTC 2023
PRIMARY
ChEMBL
CHEMBL2110871
Created by admin on Fri Dec 15 15:05:20 UTC 2023 , Edited by admin on Fri Dec 15 15:05:20 UTC 2023
PRIMARY
FDA UNII
S9P9G7VI54
Created by admin on Fri Dec 15 15:05:20 UTC 2023 , Edited by admin on Fri Dec 15 15:05:20 UTC 2023
PRIMARY
NCI_THESAURUS
C80985
Created by admin on Fri Dec 15 15:05:20 UTC 2023 , Edited by admin on Fri Dec 15 15:05:20 UTC 2023
PRIMARY
SMS_ID
100000086988
Created by admin on Fri Dec 15 15:05:20 UTC 2023 , Edited by admin on Fri Dec 15 15:05:20 UTC 2023
PRIMARY
EPA CompTox
DTXSID30178261
Created by admin on Fri Dec 15 15:05:20 UTC 2023 , Edited by admin on Fri Dec 15 15:05:20 UTC 2023
PRIMARY
EVMPD
SUB02186MIG
Created by admin on Fri Dec 15 15:05:20 UTC 2023 , Edited by admin on Fri Dec 15 15:05:20 UTC 2023
PRIMARY
CAS
23607-71-8
Created by admin on Fri Dec 15 15:05:20 UTC 2023 , Edited by admin on Fri Dec 15 15:05:20 UTC 2023
PRIMARY
NIH
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