FETOXYLATE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C36H36N2O3.ClH
Molecular Weight	581.144
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.O=C(OCCOC1=CC=CC=C1)C2(CCN(CCC(C#N)(C3=CC=CC=C3)C4=CC=CC=C4)CC2)C5=CC=CC=C5

InChI

InChIKey=DHAXFWAIZHJURV-UHFFFAOYSA-N

InChI=1S/C36H36N2O3.ClH/c37-29-36(31-15-7-2-8-16-31,32-17-9-3-10-18-32)23-26-38-24-21-35(22-25-38,30-13-5-1-6-14-30)34(39)41-28-27-40-33-19-11-4-12-20-33;/h1-20H,21-28H2;1H

HIDE SMILES / InChI

Molecular Formula	C36H36N2O3
Molecular Weight	544.6826
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6502516 | https://books.google.ru/books?id=tsjrCAAAQBAJ&pg=PA120&lpg=PA120&dq=Fetoxylate#v=onepage&q=Fetoxylate&f=false

FETOXYLATE, a phenoxyethyl ester of diphenoxylate, is an opioid receptor agonist. It is used as antidiarrheal.

Approval Year

PubMed

Title	Date	PubMed
Loperamide: blockade of calcium channels as a mechanism for antidiarrheal effects.	1984-12	6502516

Sample Use Guides

In Vitro Use Guide

The antidiarrheal opiates loperamide, fluperamide, diphenoxylate, and fetoxylate inhibited binding of [3H]nitrendipine to membranes from guinea-pig cerebral cortex with Ki values of 0.5 to 10 microM.

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:46:01 GMT 2025` Edited by `admin` on `Mon Mar 31 17:46:01 GMT 2025`
Record UNII	S9P9G7VI54
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FETOXILATE HYDROCHLORIDE

Preferred Name

English

FETOXYLATE HYDROCHLORIDE

Official Name

English

R 13,558

Code

English

FETOXYLATE HYDROCHLORIDE [USAN]

Common Name

English

MCN-JR-13558-11

Code

English

FETOXYLATE HCL

Common Name

English

4-PIPERIDINECARBOXYLIC ACID, 1-(3-CYANO-3,3-DIPHENYLPROPYL)-4-PHENYL-, 2-PHENOXYETHYL ESTER, MONOHYDROCHLORIDE

Common Name

English

MCN-JR-13,558-11

Code

English

R-13558

Code

English

Fetoxilate hydrochloride [WHO-DD]

Common Name

English

2-Phenoxyethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotate monohydrochloride

Systematic Name

English

FETOXILATE HCL

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29696