U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Nucleic Acid
Created
by admin
on Sat Dec 16 19:53:32 GMT 2023
Edited
by admin
on Sat Dec 16 19:53:32 GMT 2023
Nucleic Acid Type VECTOR
Nucleic Acid Subtype TRANSGENE
Sequence Type COMPLETE
Record UNII
S6G6VN6UWY
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Trovocabtagene autoleucel transgene insert
Common Name English
Trovocabtagene autoleucel transgene insert encoding anti-BCMA chimeric antigen receptor (CAR)
Common Name English
Code System Code Type Description
FDA UNII
S6G6VN6UWY
Created by admin on Sat Dec 16 19:53:32 GMT 2023 , Edited by admin on Sat Dec 16 19:53:32 GMT 2023
PRIMARY
Sugar Site Range Site Count
Deoxyribose (DNA) 1_1-1_4809 4809 / 4809
Linkage Site Range Site Count
Phosphate 1_2-1_4809 4808 / 4808
Name Property Type Amount Referenced Substance Defining Parameters References
anti-BCMA scFv NUCLEIC ACID FEATURE
CD8α signaling peptide NUCLEIC ACID FEATURE
WPRE NUCLEIC ACID FEATURE
SIN 5'-LTR NUCLEIC ACID FEATURE
The Rev response element (RRE) NUCLEIC ACID FEATURE
SIN 3'-LTR NUCLEIC ACID FEATURE
EF1α promoter NUCLEIC ACID FEATURE
anti-BCMA CAR NUCLEIC ACID FEATURE
packaging signal of human immunodeficiency virus type 1 (HIV-1) NUCLEIC ACID FEATURE
cPPT/CTS NUCLEIC ACID FEATURE