Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C3H6O2 |
| Molecular Weight | 74.0785 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OCCC=O
InChI
InChIKey=AKXKFZDCRYJKTF-UHFFFAOYSA-N
InChI=1S/C3H6O2/c4-2-1-3-5/h2,5H,1,3H2
| Molecular Formula | C3H6O2 |
| Molecular Weight | 74.0785 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Hydracrylaldehyde (also known as 3-hydroxypropionaldehyde or reuterin), an antimicrobial agent produced by conversion of glycerol and excreted by several bacterial species including the food grade lactic acid bacterium. Reuterin can inhibit the growth of gram-positive and gram-negative bacteria as well as yeasts, fungi, and protozoa. It was also shown that reuterin downregulated the expression of virulence genes of Helicobacter pylori, which commonly associated with gastrointestinal diseases. In addition, compound is used as a food preservative.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| In Vitro Antimicrobial Activity and Downregulation of Virulence Gene Expression on Helicobacter pylori by Reuterin. | 2018-06 |
|
| Production of reuterin in a fermented milk product by Lactobacillus reuteri: Inhibition of pathogens, spoilage microorganisms, and lactic acid bacteria. | 2017-06 |
|
| Optimization of reuterin production in cheese by Lactobacillus reuteri. | 2017-04 |
|
| Crosslinked, cryostructured Lactobacillus reuteri monoliths for production of 3-hydroxypropionaldehyde, 3-hydroxypropionic acid and 1,3-propanediol from glycerol. | 2017-01-10 |
|
| 3-hydroxypropionaldehyde: applications and perspectives of biotechnological production. | 2004-03 |
|
| Chemical characterization of an antimicrobial substance produced by Lactobacillus reuteri. | 1989-05 |
Sample Use Guides
In a reuterin bacterial killing assay, it was observed that half of the MIC value for H. pylori (ATCC700824) significantly (P < 0.01) reduced colony numbers from 5.65 ± 0.35 to 3.78 ± 0.35 Log10 CFU/mL after 12 h of treatment and then increased them to 5.25 ± 0.23 Log10 CFU/mL at 24 h; at its MIC value (20.48 mM), reuterin abrogated (P < 0.01) H. pylori (ATCC700824) growth after 20 h of culture
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:58:54 GMT 2025
by
admin
on
Mon Mar 31 19:58:54 GMT 2025
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| Record UNII |
S5F79YAO6U
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| Record Status |
Validated (UNII)
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| Record Version |
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