TRIPHENYLETHYLENE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H16
Molecular Weight	256.341
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C(=C(C1=CC=CC=C1)C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=MKYQPGPNVYRMHI-UHFFFAOYSA-N

InChI=1S/C20H16/c1-4-10-17(11-5-1)16-20(18-12-6-2-7-13-18)19-14-8-3-9-15-19/h1-16H

HIDE SMILES / InChI

Molecular Formula	C20H16
Molecular Weight	256.341
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Cone voltage and collision cell collision-induced dissociation study of triphenylethylenes of pharmaceutical interest.	2001	11544585
Endocrine manipulation in advanced breast cancer: recent advances with SERM therapies.	2001 Dec	11916228
Differential SERM activation of the estrogen receptors (ERalpha and ERbeta) at AP-1 sites.	2001 May	11358690
Triphenylethylene antiestrogen-induced acute relaxation of mouse duodenal muscle. Possible involvement of Ca2+ channels.	2002 Jun 12	12079691
Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.	2003 Oct	14565775
Selective estrogen receptor modulators inhibit growth and progression of premalignant lesions in a mouse model of ductal carcinoma in situ.	2005	16280035
Dielectric and shear mechanical alpha and beta relaxations in seven glass-forming liquids.	2005 Dec 15	16392935
Investigation of radical cation in electrophilic fluorination by ESI-MS.	2005 Sep 1	16119921
Additive growth inhibitory effects of ibandronate and antiestrogens in estrogen receptor-positive breast cancer cell lines.	2006	16417650
Functional inhibition of intestinal and uterine muscles by non-permeant triphenylethylene derivatives.	2006 Feb 17	16466652
Modulation of estrogen receptor transactivation and estrogen-induced gene expression by ormeloxifene-a triphenylethylene derivative.	2006 Nov	16965798
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006 Nov	16497524
Effects of tamoxifen on vaginal blood flow and epithelial morphology in the rat.	2006 Sep 13	16970814
The differential effects of bisphosphonates, SERMS (selective estrogen receptor modulators), and parathyroid hormone on bone remodeling in osteoporosis.	2007	18044075
Estrogenic or antiestrogenic therapies for multiple myeloma?	2007 Sep 24	17888187
By looking back we can see the way forward: enhancing the gains achieved with antihormone therapy.	2008	19128429
Female sex hormones mediate the allergic lung reaction by regulating the release of inflammatory mediators and the expression of lung E-selectin in rats.	2010 Aug 24	20735828
Anti-breast cancer potential of SS1020, a novel antiestrogen lacking estrogenic and genotoxic actions.	2010 Oct 1	20073065

Substance Class	Chemical Created by `admin` on `Sat Dec 16 02:15:40 GMT 2023` Edited by `admin` on `Sat Dec 16 02:15:40 GMT 2023`
Record UNII	S4ZLZ1K74B
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TRIPHENYLETHYLENE

Systematic Name

English

NSC-17535

Code

English

ETHYLENE, TRIPHENYL-

Systematic Name

English

1,1,2-TRIPHENYLETHENE

Systematic Name

English

TRIPHENYLETHENE

Systematic Name

English

1,1,2-TRIPHENYLETHYLENE

Systematic Name

English

BENZILIDENEDIPHENYLMETHANE

Common Name

English

BENZENE, 1,1',1''-(1-ETHENYL-2-YLIDENE)TRIS-

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C553