TASULDINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H9N3S
Molecular Weight	203.264
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C(SC1=NC=CC=N1)C2=CC=CN=C2

InChI

InChIKey=HMCTXMOKMWELFJ-UHFFFAOYSA-N

InChI=1S/C10H9N3S/c1-3-9(7-11-4-1)8-14-10-12-5-2-6-13-10/h1-7H,8H2

HIDE SMILES / InChI

Molecular Formula	C10H9N3S
Molecular Weight	203.264
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/9778490 | Elks J., The Dictionary of Drugs: Chemical Data: Chemical Data, Structures, p. 1150, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ&pg=PA1150&lpg=PA1150&dq=TASULDINE&source=bl&ots=6JUgp7ZDrz&sig=ACfU3U3Sz4VwhYN6vhWE0YHBto0KES9rrg&hl=ru&sa=X&ved=2ahUKEwjT-9vGqZzjAhVKK5oKHWetCOg4FBDoATADegQICBAB#v=onepage&q=TASULDINE&f=false

Tasuldine is as an orally active bronchosecretolytic agent that was clinically effective in human. However, information about the further development and use of this drug is not available.

Approval Year

PubMed

Title	Date	PubMed
Influence of tasuldine and acetylcysteine on mucociliary clearance in patients with chronic airways obstruction.	1986	3954815
2-[(3-Pyridinylmethyl)thio]pyrimidine derivatives: new bronchosecretolytic agents.	1987 Mar	3820227
The effect of tasuldine, a bronchosecretolytic agent, on mucus rheology and clearability and the interaction with acetylcholine in ferrets.	1997 Oct-Dec	9778490

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:16:02 GMT 2023` Edited by `admin` on `Sat Dec 16 16:16:02 GMT 2023`
Record UNII	S4ZCE64Q3O
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TASULDINE

Official Name

English

tasuldine [INN]

Common Name

English

TASULDINE [MART.]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C74536