U.S. Department of Health & Human Services
National Institutes of Health
NCATS
This repository is under review for potential modification in compliance with Administration directives.
Dismiss
Return Home
Inxight
Drugs
Search Substances
Home
Browse Drugs
US Approved Drugs
Marketed Drugs
Investigational Drugs
All Substances
Search
Structure Search
Sequence Search
Downloads
About
Search Substances
SHR-1501
S4NL6N7DWD
Other
General
Record Details
Names
4
Identifiers
2
Concept Definition
Relationships
1
Active Moiety
1
SHR-1501
S4NL6N7DWD
Other
General
Approval Year
Unknown
149,124
Record Details
Substance Class
Concept
Record UNII
S4NL6N7DWD
Record Status
Validated (UNII)
Record Version
5
4
3
2
1
Names
4
Show
5
20
100
All
entries
Name
Type
Language
Name
Type
Language
IL-15 Super-agonist SHR1501
Preferred Name
English
SHR-1501
Code
English
Interleukin-15 Agonist Fusion Protein SHR1501
Common Name
English
SHR-1501(human Fc fusion protein composed of the cytokine interleukin (IL)-15 cross-linked with the high-affinity binding sushi domain of IL-15 receptor alpha (IL-15Ra))
Common Name
English
Showing 1 to 4 of 4 entries
Previous
1
Next
Identifiers
2
Show
5
20
100
All
entries
Code System
Code
Type
Description
Code System
Code
Type
Description
NCI_THESAURUS
C171385
PRIMARY
FDA UNII
S4NL6N7DWD
PRIMARY
Showing 1 to 2 of 2 entries
Previous
1
Next
Concept Definition
This is a non-substance concept
Relationships
1
Show
5
20
100
All
entries
Related Record
Type
Details
Related Record
Type
Details
DN82J7Z829
Interleukin-2 receptor subunit beta and gamma complex
TARGET -> AGONIST
Comments:
SHR-1501 activates and increases the levels of natural killer (NK) cells and memory CD8+ T-cells without stimulating regulatory T-cells (Tregs).
Amount:
Showing 1 to 1 of 1 entries
Previous
1
Next
Active Moiety
1
Show
5
20
100
All
entries
Related Record
Type
Details
Related Record
Type
Details
S4NL6N7DWD
SHR-1501
ACTIVE MOIETY
Amount:
Showing 1 to 1 of 1 entries
Previous
1
Next
This is a non-substance concept