Approval Year
| Substance Class |
Structurally Diverse
Created
by
admin
on
Edited
Sat Dec 16 15:12:36 GMT 2023
by
admin
on
Sat Dec 16 15:12:36 GMT 2023
|
| Source Materials Class | ORGANISM |
| Source Materials Type | VIRUS |
| Source Materials State | LIVE GENETICALLY MODIFIED NON-REPLICATING |
| Source Materials Parent | |
| Organism Family | Adenoviridae |
| Organism Genus | Mastadenovirus |
| Organism Species | human mastadenovirus c |
| Infraspecific Type | SEROTYPE |
| Infraspecific Name | TYPE 5 |
| Part | WHOLE |
| Record UNII |
S4MK9TOL0D
|
| Record Status |
Validated (UNII)
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| Record Version |
|
-
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
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C150517
Created by
admin on Sat Dec 16 15:12:36 GMT 2023 , Edited by admin on Sat Dec 16 15:12:36 GMT 2023
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PRIMARY | |||
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S4MK9TOL0D
Created by
admin on Sat Dec 16 15:12:36 GMT 2023 , Edited by admin on Sat Dec 16 15:12:36 GMT 2023
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PRIMARY | |||
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2171509-20-7
Created by
admin on Sat Dec 16 15:12:36 GMT 2023 , Edited by admin on Sat Dec 16 15:12:36 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
TARGET->ANTIGEN |
Identified as a definitive diagnostic marker, key driver and therapeutic target for chordoma, a malignant tumor that arises from remnant notochordal cells lodged in the vertebrae
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
Structural Modifications
| Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
|---|---|---|---|---|---|---|
| PROTEIN NOT EXPRESSED (GENE DISRUPTION) | viral genes early 1 | EARLY E1A PROTEIN (HUMAN ADENOVIRUS 5) | MW6YY4WVP4 | |||
| VECTOR EXPRESSED PROTEIN | UNKNOWN | RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2 | 7J9Y28299R | |||
| PROTEIN NOT EXPRESSED (GENE DISRUPTION) | viral genes early 2b | DNA POLYMERASE (HUMAN ADENOVIRUS 5) | ETQ2WKD05X | |||
| PROTEIN NOT EXPRESSED (GENE DISRUPTION) | viral genes early 2b | PRETERMINAL PROTEIN (HUMAN ADENOVIRUS 5) | PL0VT48B2N |