TEPLIZUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 00:21:45 UTC 2023` Edited by `admin` on `Sat Dec 16 00:21:45 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	S4M959U2IJ
Record Status	`Validated (UNII)`
Record Version

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Related Record	Type

Name

Type

Language

TEPLIZUMAB

Official Name

English

HUMANZIED OKT3

Code

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN CD3 (ANTIGEN).EPSILON.-CHAIN)(HUMAN-MOUSE MONOCLONAL MGA031 HEAVY CHAIN), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL MGA031 LIGHT-CHAIN DIMER

Common Name

English

MGA-031

Code

English

PRV031

Code

English

HOKT3 GAMMA 1 (ALA-ALA)

Code

English

teplizumab [INN]

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN) HUMANIZED MOUSE MONOCLONAL MGA031; GAMMA1 HEAVY CHAIN (HUMANIZED VH (HOMO SAPIENS FR/MUS MUSCULUS CDR)-(117-ALANINE,118-ALANINE)HOMO SAPIENS IGHG1) (222-213')-DISULFIDE WITH KA

Common Name

English

PRV-031

Code

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN CD3 (ANTIGEN).EPSILON.-CHAIN)(HUMAN-MOUSE MONOCLONAL MGA031 HEAVY CHAIN), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL MGA031 LIGHT-CHAIN DIMER

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN) HUMANIZED MOUSE MONOCLONAL MGA031; GAMMA1 HEAVY CHAIN (HUMANIZED VH (HOMO SAPIENS FR/MUS MUSCULUS CDR)-(117-ALANINE,118-ALANINE)HOMO SAPIENS IGHG1) (222-213')-DISULPHIDE WITH K

Common Name

English

MGA031

Code

English

TEPLIZUMAB [USAN]

Common Name

English

Teplizumab [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C20401

Created by admin on Sat Dec 16 00:21:45 UTC 2023 , Edited by admin on Sat Dec 16 00:21:45 UTC 2023

FDA ORPHAN DRUG

229606

Created by admin on Sat Dec 16 00:21:45 UTC 2023 , Edited by admin on Sat Dec 16 00:21:45 UTC 2023

Code System Code Type Description

NCI_THESAURUS

C88647

Created by admin on Sat Dec 16 00:21:45 UTC 2023 , Edited by admin on Sat Dec 16 00:21:45 UTC 2023

PRIMARY

INN

8869

Created by admin on Sat Dec 16 00:21:45 UTC 2023 , Edited by admin on Sat Dec 16 00:21:45 UTC 2023

PRIMARY

USAN

SS-101

Created by admin on Sat Dec 16 00:21:45 UTC 2023 , Edited by admin on Sat Dec 16 00:21:45 UTC 2023

PRIMARY

DAILYMED

S4M959U2IJ

Created by admin on Sat Dec 16 00:21:45 UTC 2023 , Edited by admin on Sat Dec 16 00:21:45 UTC 2023

PRIMARY

CAS

876387-05-2

Created by admin on Sat Dec 16 00:21:45 UTC 2023 , Edited by admin on Sat Dec 16 00:21:45 UTC 2023

PRIMARY

FDA UNII

S4M959U2IJ

Created by admin on Sat Dec 16 00:21:45 UTC 2023 , Edited by admin on Sat Dec 16 00:21:45 UTC 2023

PRIMARY

RXCUI

2621880

Created by admin on Sat Dec 16 00:21:45 UTC 2023 , Edited by admin on Sat Dec 16 00:21:45 UTC 2023

PRIMARY

ChEMBL

CHEMBL1743078

Created by admin on Sat Dec 16 00:21:45 UTC 2023 , Edited by admin on Sat Dec 16 00:21:45 UTC 2023

PRIMARY

WIKIPEDIA

TEPLIZUMAB

Created by admin on Sat Dec 16 00:21:45 UTC 2023 , Edited by admin on Sat Dec 16 00:21:45 UTC 2023

PRIMARY

EVMPD

SUB35383

Created by admin on Sat Dec 16 00:21:45 UTC 2023 , Edited by admin on Sat Dec 16 00:21:45 UTC 2023

PRIMARY

DRUG BANK

DB06606

Created by admin on Sat Dec 16 00:21:45 UTC 2023 , Edited by admin on Sat Dec 16 00:21:45 UTC 2023

PRIMARY

From	To
1_22	1_96
1_146	1_202
1_222	3_213
1_228	2_228
1_231	2_231
1_263	1_323
1_369	1_427
2_22	2_96
2_146	2_202
2_222	4_213
2_263	2_323
2_369	2_427
3_23	3_87
3_133	3_193
4_23	4_87
4_133	4_193

Related Record Type Details

Teplizumab-MZWV

SUB_CONCEPT->SUBSTANCE

Amount:

Related Record Type Details


					S4M959U2IJ

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:SEQUENCE	CHEMICAL
Molecular Formula	CHEMICAL