U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 00:21:45 GMT 2023
Edited
by admin
on Sat Dec 16 00:21:45 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
S4M959U2IJ
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
TEPLIZUMAB
INN   USAN   WHO-DD  
INN   USAN  
Official Name English
HUMANZIED OKT3
Code English
IMMUNOGLOBULIN G1, ANTI-(HUMAN CD3 (ANTIGEN).EPSILON.-CHAIN)(HUMAN-MOUSE MONOCLONAL MGA031 HEAVY CHAIN), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL MGA031 LIGHT-CHAIN DIMER
Common Name English
MGA-031
Code English
PRV031
Code English
HOKT3 GAMMA 1 (ALA-ALA)
Code English
teplizumab [INN]
Common Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN) HUMANIZED MOUSE MONOCLONAL MGA031; GAMMA1 HEAVY CHAIN (HUMANIZED VH (HOMO SAPIENS FR/MUS MUSCULUS CDR)-(117-ALANINE,118-ALANINE)HOMO SAPIENS IGHG1) (222-213')-DISULFIDE WITH KA
Common Name English
PRV-031
Code English
IMMUNOGLOBULIN G1, ANTI-(HUMAN CD3 (ANTIGEN).EPSILON.-CHAIN)(HUMAN-MOUSE MONOCLONAL MGA031 HEAVY CHAIN), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL MGA031 LIGHT-CHAIN DIMER
Common Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN) HUMANIZED MOUSE MONOCLONAL MGA031; GAMMA1 HEAVY CHAIN (HUMANIZED VH (HOMO SAPIENS FR/MUS MUSCULUS CDR)-(117-ALANINE,118-ALANINE)HOMO SAPIENS IGHG1) (222-213')-DISULPHIDE WITH K
Common Name English
MGA031
Code English
TEPLIZUMAB [USAN]
Common Name English
Teplizumab [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C20401
Created by admin on Sat Dec 16 00:21:45 GMT 2023 , Edited by admin on Sat Dec 16 00:21:45 GMT 2023
FDA ORPHAN DRUG 229606
Created by admin on Sat Dec 16 00:21:45 GMT 2023 , Edited by admin on Sat Dec 16 00:21:45 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C88647
Created by admin on Sat Dec 16 00:21:45 GMT 2023 , Edited by admin on Sat Dec 16 00:21:45 GMT 2023
PRIMARY
INN
8869
Created by admin on Sat Dec 16 00:21:45 GMT 2023 , Edited by admin on Sat Dec 16 00:21:45 GMT 2023
PRIMARY
USAN
SS-101
Created by admin on Sat Dec 16 00:21:45 GMT 2023 , Edited by admin on Sat Dec 16 00:21:45 GMT 2023
PRIMARY
DAILYMED
S4M959U2IJ
Created by admin on Sat Dec 16 00:21:45 GMT 2023 , Edited by admin on Sat Dec 16 00:21:45 GMT 2023
PRIMARY
CAS
876387-05-2
Created by admin on Sat Dec 16 00:21:45 GMT 2023 , Edited by admin on Sat Dec 16 00:21:45 GMT 2023
PRIMARY
FDA UNII
S4M959U2IJ
Created by admin on Sat Dec 16 00:21:45 GMT 2023 , Edited by admin on Sat Dec 16 00:21:45 GMT 2023
PRIMARY
RXCUI
2621880
Created by admin on Sat Dec 16 00:21:45 GMT 2023 , Edited by admin on Sat Dec 16 00:21:45 GMT 2023
PRIMARY
ChEMBL
CHEMBL1743078
Created by admin on Sat Dec 16 00:21:45 GMT 2023 , Edited by admin on Sat Dec 16 00:21:45 GMT 2023
PRIMARY
WIKIPEDIA
TEPLIZUMAB
Created by admin on Sat Dec 16 00:21:45 GMT 2023 , Edited by admin on Sat Dec 16 00:21:45 GMT 2023
PRIMARY
EVMPD
SUB35383
Created by admin on Sat Dec 16 00:21:45 GMT 2023 , Edited by admin on Sat Dec 16 00:21:45 GMT 2023
PRIMARY
DRUG BANK
DB06606
Created by admin on Sat Dec 16 00:21:45 GMT 2023 , Edited by admin on Sat Dec 16 00:21:45 GMT 2023
PRIMARY
From To
1_22 1_96
1_146 1_202
1_222 3_213
1_228 2_228
1_231 2_231
1_263 1_323
1_369 1_427
2_22 2_96
2_146 2_202
2_222 4_213
2_263 2_323
2_369 2_427
3_23 3_87
3_133 3_193
4_23 4_87
4_133 4_193
Related Record Type Details
SUB_CONCEPT->SUBSTANCE
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:SEQUENCE CHEMICAL
Molecular Formula CHEMICAL