Sericoside Phytosome is a patent complex between Sericoside and soy phospholipids. Terminalia sericea, from which Sericoside was isolated and extracted for the frst time by Indena, has been traditionally used in Africa and Asia for the treatment of severe skin diseases. The adjective sericea, in ancient Latin, means “silky, smooth as silk”. Sericoside Phytosome 0.5% emulsion was applied twice daily for 42 days on all wrinkles called crow's feet, reproducing normal conditions of use. The product showed to be efficacious in over 70% of the tested female subjects, accomplishing a reduction in wrinkles depth and total wrinkled surface. Many trials have been performed and Sericoside has shown to have skin-restructuring, capillary protecting activity, wound healing and anti-oedema properties. This is due to a remarkable reduction of capillary permeability exerted by the active ingredient.