KW-7158

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C16H12F3NO5S2
Molecular Weight	419.395
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[C@](O)(C(=O)NC1=C2C(=CC=C1)S(=O)(=O)CC3=C(SC=C3)C2=O)C(F)(F)F

InChI

InChIKey=NAFSYPCVPLWHFY-HNNXBMFYSA-N

InChI=1S/C16H12F3NO5S2/c1-15(23,16(17,18)19)14(22)20-9-3-2-4-10-11(9)12(21)13-8(5-6-26-13)7-27(10,24)25/h2-6,23H,7H2,1H3,(H,20,22)/t15-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C16H12F3NO5S2
Molecular Weight	419.395
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Kv4 Channels Underlie the Subthreshold-Operating A-type K-current in Nociceptive Dorsal Root Ganglion Neurons.	2009	19668710

Substance Class	Chemical Created by `admin` on `Sat Dec 16 09:08:42 GMT 2023` Edited by `admin` on `Sat Dec 16 09:08:42 GMT 2023`
Record UNII	S2T07V1P1G
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

KW-7158

Common Name

English

(+)-KW-7158

Common Name

English

PROPANAMIDE, N-(4,10-DIHYDRO-5,5-DIOXIDO-10-OXOTHIENO(3,2-C)(1)BENZOTHIEPIN-9-YL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYL-, (2S)-

Systematic Name

English

(S)-5,5-DIOXO-9-((3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL)AMINO)-4,10-DIHYDROTHIENO(3,2-C)(1)BENZOTHIEPIN-10-ONE

Systematic Name

English

Code System Code Type Description

CAS

214764-26-8

Created by admin on Sat Dec 16 09:08:42 GMT 2023 , Edited by admin on Sat Dec 16 09:08:42 GMT 2023

PRIMARY

DRUG BANK

DB05498

Created by admin on Sat Dec 16 09:08:42 GMT 2023 , Edited by admin on Sat Dec 16 09:08:42 GMT 2023

PRIMARY

PUBCHEM

9844981

Created by admin on Sat Dec 16 09:08:42 GMT 2023 , Edited by admin on Sat Dec 16 09:08:42 GMT 2023

PRIMARY

FDA UNII

S2T07V1P1G

Created by admin on Sat Dec 16 09:08:42 GMT 2023 , Edited by admin on Sat Dec 16 09:08:42 GMT 2023

PRIMARY

Related Record Type Details


					J4K79C5KL9

THIENO(3,2-C)(1)BENZOTHIEPIN-10(4H)-ONE, 9-AMINO-, 5,5-DIOXIDE

METABOLITE INACTIVE -> PARENT

Comments:

MINOR METABOLITE IN RODENTS AND DOGS

Interaction Type:

MAJOR

Qualification:

PLASMA


					MQ8HCI2333

N-(4,10-DIHYDRO-5,5-DIOXIDO-10-OXO(1)BENZOTHIEPINO(4,3-B)FURAN-9-YL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE, (2S)-

METABOLITE -> PARENT

Comments:

MAJOR METABOLITE IN RODENTS AND DOGS

Interaction Type:

MINOR

Qualification:

PLASMA

Related Record Type Details


					S2T07V1P1G

KW-7158

ACTIVE MOIETY