Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C16H12F3NO5S2 |
| Molecular Weight | 419.395 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@](O)(C(=O)NC1=C2C(=CC=C1)S(=O)(=O)CC3=C(SC=C3)C2=O)C(F)(F)F
InChI
InChIKey=NAFSYPCVPLWHFY-HNNXBMFYSA-N
InChI=1S/C16H12F3NO5S2/c1-15(23,16(17,18)19)14(22)20-9-3-2-4-10-11(9)12(21)13-8(5-6-26-13)7-27(10,24)25/h2-6,23H,7H2,1H3,(H,20,22)/t15-/m0/s1
| Molecular Formula | C16H12F3NO5S2 |
| Molecular Weight | 419.395 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Kv4 Channels Underlie the Subthreshold-Operating A-type K-current in Nociceptive Dorsal Root Ganglion Neurons. | 2009 |
|
| KW-7158 [(2S)-(+)-3,3,3-trifluoro-2-hydroxy-2-methyl-N-(5,5,10-trioxo-4,10-dihydrothieno[3,2-c][1]benzothiepin-9-yl)propanamide] enhances A-type K+ currents in neurons of the dorsal root ganglion of the adult rat. | 2004-07 |
|
| Effect of KW-7158, a putative afferent nerve inhibitor, on bladder and vesico-vascular reflexes in rats. | 2002-08-09 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:31:03 GMT 2025
by
admin
on
Mon Mar 31 22:31:03 GMT 2025
|
| Record UNII |
S2T07V1P1G
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
214764-26-8
Created by
admin on Mon Mar 31 22:31:03 GMT 2025 , Edited by admin on Mon Mar 31 22:31:03 GMT 2025
|
PRIMARY | |||
|
DB05498
Created by
admin on Mon Mar 31 22:31:03 GMT 2025 , Edited by admin on Mon Mar 31 22:31:03 GMT 2025
|
PRIMARY | |||
|
9844981
Created by
admin on Mon Mar 31 22:31:03 GMT 2025 , Edited by admin on Mon Mar 31 22:31:03 GMT 2025
|
PRIMARY | |||
|
S2T07V1P1G
Created by
admin on Mon Mar 31 22:31:03 GMT 2025 , Edited by admin on Mon Mar 31 22:31:03 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
METABOLITE INACTIVE -> PARENT |
MINOR METABOLITE IN RODENTS AND DOGS
MAJOR
PLASMA
|
||
|
METABOLITE -> PARENT |
MAJOR METABOLITE IN RODENTS AND DOGS
MINOR
PLASMA
|
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |
