U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 14:43:47 GMT 2023
Edited
by admin
on Sat Dec 16 14:43:47 GMT 2023
Source Materials Class ORGANISM
Source Materials Type BACTERIUM
Source Materials State LIVE ATTENUATED
Source Materials Parent
Organism Family Listeriaceae
Organism Genus Listeria
Organism Species monocytogenes
Author NONE
Infraspecific Type STRAIN
Infraspecific Name .DELTA.actA/.DELTA.nlB/EGFRvIII-hMeso strain PL1304
Part WHOLE
Record UNII
S2EGO8116S
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PEMLIMOGENE MEROLISBAC
INN   USAN  
Official Name English
LADD LISTERIA MONOCYTOGENES JNJ-64041757
Common Name English
LIVE-ATTENUATED LISTERIA MONOCYTOGENES ENCODING EGFRVIII-MESOTHELIN VACCINE JNJ-64041757
Common Name English
RECOMBINANT LIVE-ATTENUATED DOUBLE-DELETED (LADD) STRAIN OF LISTERIA MONOCYTOGENES (LM .DELTA.ACTA/.DELTA.INLB) EXPRESSING A FUSION PROTEIN COMPRISING THE N-TERMINAL 100 AMINO ACIDS OF THE LM ACTA PROTEIN (ACTAN100), 5 TANDEM COPIES OF A 21 AMINO ACID FR
Systematic Name English
JNJ-64041757
Code English
ADU-214
Code English
Pemlimogene merolisbac [WHO-DD]
Common Name English
pemlimogene merolisbac [INN]
Common Name English
PEMLIMOGENE MEROLISBAC [USAN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C1663
Created by admin on Sat Dec 16 14:43:47 GMT 2023 , Edited by admin on Sat Dec 16 14:43:47 GMT 2023
NCI_THESAURUS C62761
Created by admin on Sat Dec 16 14:43:47 GMT 2023 , Edited by admin on Sat Dec 16 14:43:47 GMT 2023
Code System Code Type Description
FDA UNII
S2EGO8116S
Created by admin on Sat Dec 16 14:43:47 GMT 2023 , Edited by admin on Sat Dec 16 14:43:47 GMT 2023
PRIMARY
INN
10546
Created by admin on Sat Dec 16 14:43:47 GMT 2023 , Edited by admin on Sat Dec 16 14:43:47 GMT 2023
PRIMARY
NCI_THESAURUS
C124843
Created by admin on Sat Dec 16 14:43:47 GMT 2023 , Edited by admin on Sat Dec 16 14:43:47 GMT 2023
PRIMARY
USAN
FG-96
Created by admin on Sat Dec 16 14:43:47 GMT 2023 , Edited by admin on Sat Dec 16 14:43:47 GMT 2023
PRIMARY
Related Record Type Details
TARGET->ANTIGEN
TARGET->ANTIGEN
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
GENE DELETION Amount: LISTERIA MONOCYTOGENES ACT-A GENE 5G6813094G
VECTOR EXPRESSED PROTEIN UNSPECIFIED SUBSTANCE
6dbca1b8
(not in database)
GENE DELETION Amount: LISTERIA MONOCYTOGENES INI-B GENE O374421TMO