SYMETINE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C30H48N2O2.2ClH
Molecular Weight	541.636
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.Cl.CCCCCCN(C)CC1=CC=C(OCCOC2=CC=C(CN(C)CCCCCC)C=C2)C=C1

InChI

InChIKey=AVQAMDIAGIHYPS-UHFFFAOYSA-N

InChI=1S/C30H48N2O2.2ClH/c1-5-7-9-11-21-31(3)25-27-13-17-29(18-14-27)33-23-24-34-30-19-15-28(16-20-30)26-32(4)22-12-10-8-6-2;;/h13-20H,5-12,21-26H2,1-4H3;2*1H

HIDE SMILES / InChI

Molecular Formula	C30H48N2O2
Molecular Weight	468.7143
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/15445946 | https://www.ncbi.nlm.nih.gov/pubmed/24543175 | Antibiotics and Chemotherapy (Washington, D. C.) (1954), 4, 753-62.

Symetine is a benzylamine derivative patented by Eli Lilly & Co. as an antiparasitic and antispirochete agent. In preclinical models, Symetine effectively suppresses amebic liver abscess in guinea pigs.

Originator

Approval Year

PubMed

Title	Date	PubMed

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:28:27 GMT 2023` Edited by `admin` on `Fri Dec 15 16:28:27 GMT 2023`
Record UNII	S175C652YS
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SYMETINE HYDROCHLORIDE

Official Name

English

BENZENEMETHANAMINE, 4,4'-(1,2-ETHANEDIYLBIS(OXY))BIS(N-HEXYL-N-METHYL-, DIHYDROCHLORIDE

Common Name

English

SYMETINE HCL

Common Name

English

SYMETINE HYDROCHLORIDE [USAN]

Common Name

English

BENZENEMETHANAMINE, 4,4'-(1,2-ETHANEDIYLBIS(OXY))BIS(N-HEXYL-N-METHYL-, HYDROCHLORIDE (1:2)

Systematic Name

English

4,4'-(ETHYLENEDIOXY)BIS(N-HEXYL-N-METHYLBENZYLAMINE) DIHYDROCHLORIDE

Systematic Name

English

NSC-81908

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C737