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Details

Stereochemistry UNKNOWN
Molecular Formula C11H12Cl3N
Molecular Weight 264.579
Optical Activity ( - )
Defined Stereocenters 0 / 1
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of AMFECLORAL, (-)-

SMILES

CC(CC1=CC=CC=C1)\N=C\C(Cl)(Cl)Cl

InChI

InChIKey=VBZDETYCYXPOAK-OVCLIPMQSA-N
InChI=1S/C11H12Cl3N/c1-9(15-8-11(12,13)14)7-10-5-3-2-4-6-10/h2-6,8-9H,7H2,1H3/b15-8+

HIDE SMILES / InChI

Molecular Formula C11H12Cl3N
Molecular Weight 264.579
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 1
Optical Activity ( + / - )

Amphecloral (INN: amfecloral) is a phenethylamine derivative which was patented in 1960 as an amphetamine pro-drug with prolonged duration of action. Amfecloral was used as an appetite suppressant under the trade name Acutran, but is now no longer marketed. It is an anorectic drug with little to no stimulant activity. Amphecloral is metabolized to both d-(S)- and l-(R)-amphetamine.

Approval Year

PubMed

PubMed

TitleDatePubMed
Chiral toxicology: it's the same thing...only different.
2009-07
Mode of action of psychomotor stimulant drugs.
1970
Patents
Substance Class Chemical
Created
by admin
on Wed Apr 02 12:15:37 GMT 2025
Edited
by admin
on Wed Apr 02 12:15:37 GMT 2025
Record UNII
S0DYI19OEX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
(-)-AMFECLORAL
Preferred Name English
AMFECLORAL, (-)-
Common Name English
BENZENEETHANAMINE, .ALPHA.-METHYL-N-(2,2,2-TRICHLOROETHYLIDENE)-, (-)-
Systematic Name English
Code System Code Type Description
FDA UNII
S0DYI19OEX
Created by admin on Wed Apr 02 12:15:37 GMT 2025 , Edited by admin on Wed Apr 02 12:15:37 GMT 2025
PRIMARY
CAS
71528-69-3
Created by admin on Wed Apr 02 12:15:37 GMT 2025 , Edited by admin on Wed Apr 02 12:15:37 GMT 2025
PRIMARY
Related Record Type Details
RACEMATE -> ENANTIOMER