OLACAFTOR

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C29H34FN3O4S
Molecular Weight	539.661
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of OLACAFTOR

Structure Search

SMILES

CC(C)COC1=CC(F)=CC(=C1)C2=CC=C(C(=O)NS(=O)(=O)C3=CC=CC=C3)C(=N2)N4C[C@@H](C)CC4(C)C

InChI

InChIKey=NHOUNZMCSIHKHJ-FQEVSTJZSA-N

InChI=1S/C29H34FN3O4S/c1-19(2)18-37-23-14-21(13-22(30)15-23)26-12-11-25(27(31-26)33-17-20(3)16-29(33,4)5)28(34)32-38(35,36)24-9-7-6-8-10-24/h6-15,19-20H,16-18H2,1-5H3,(H,32,34)/t20-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C29H34FN3O4S
Molecular Weight	539.661
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 13:43:03 GMT 2023` Edited by `admin` on `Sat Dec 16 13:43:03 GMT 2023`
Record UNII	RZ7027HK8F
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

OLACAFTOR

Official Name

English

6-[3-Fluoro-5-(2-methylpropoxy)phenyl]-N-(phenylsulfonyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide

Systematic Name

English

olacaftor [INN]

Common Name

English

VX-440

Code

English

OLACAFTOR [USAN]

Common Name

English

3-PYRIDINECARBOXAMIDE, 6-(3-FLUORO-5-(2-METHYLPROPOXY)PHENYL)-N-(PHENYLSULFONYL)-2-((4S)-2,2,4-TRIMETHYL-1-PYRROLIDINYL)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

121250885

Created by admin on Sat Dec 16 13:43:04 GMT 2023 , Edited by admin on Sat Dec 16 13:43:04 GMT 2023

PRIMARY

CAS

1897384-89-2

Created by admin on Sat Dec 16 13:43:04 GMT 2023 , Edited by admin on Sat Dec 16 13:43:04 GMT 2023

PRIMARY

SMS_ID

100000183596

Created by admin on Sat Dec 16 13:43:04 GMT 2023 , Edited by admin on Sat Dec 16 13:43:04 GMT 2023

PRIMARY

INN

10886

Created by admin on Sat Dec 16 13:43:04 GMT 2023 , Edited by admin on Sat Dec 16 13:43:04 GMT 2023

PRIMARY

USAN

EF-134

Created by admin on Sat Dec 16 13:43:04 GMT 2023 , Edited by admin on Sat Dec 16 13:43:04 GMT 2023

PRIMARY

NCI_THESAURUS

C170243

Created by admin on Sat Dec 16 13:43:04 GMT 2023 , Edited by admin on Sat Dec 16 13:43:04 GMT 2023

PRIMARY

FDA UNII

RZ7027HK8F

Created by admin on Sat Dec 16 13:43:04 GMT 2023 , Edited by admin on Sat Dec 16 13:43:04 GMT 2023

PRIMARY

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