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Details

Stereochemistry ABSOLUTE
Molecular Formula C29H34FN3O4S
Molecular Weight 539.661
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of OLACAFTOR

SMILES

CC(C)COC1=CC(F)=CC(=C1)C2=CC=C(C(=O)NS(=O)(=O)C3=CC=CC=C3)C(=N2)N4C[C@@H](C)CC4(C)C

InChI

InChIKey=NHOUNZMCSIHKHJ-FQEVSTJZSA-N
InChI=1S/C29H34FN3O4S/c1-19(2)18-37-23-14-21(13-22(30)15-23)26-12-11-25(27(31-26)33-17-20(3)16-29(33,4)5)28(34)32-38(35,36)24-9-7-6-8-10-24/h6-15,19-20H,16-18H2,1-5H3,(H,32,34)/t20-/m0/s1

HIDE SMILES / InChI

Molecular Formula C29H34FN3O4S
Molecular Weight 539.661
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Substance Class Chemical
Created
by admin
on Thu Jul 06 19:22:04 UTC 2023
Edited
by admin
on Thu Jul 06 19:22:04 UTC 2023
Record UNII
RZ7027HK8F
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
OLACAFTOR
INN   USAN  
Official Name English
6-[3-Fluoro-5-(2-methylpropoxy)phenyl]-N-(phenylsulfonyl)-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide
Systematic Name English
olacaftor [INN]
Common Name English
VX-440
Code English
OLACAFTOR [USAN]
Common Name English
3-PYRIDINECARBOXAMIDE, 6-(3-FLUORO-5-(2-METHYLPROPOXY)PHENYL)-N-(PHENYLSULFONYL)-2-((4S)-2,2,4-TRIMETHYL-1-PYRROLIDINYL)-
Systematic Name English
Code System Code Type Description
PUBCHEM
121250885
Created by admin on Thu Jul 06 19:22:05 UTC 2023 , Edited by admin on Thu Jul 06 19:22:05 UTC 2023
PRIMARY
CAS
1897384-89-2
Created by admin on Thu Jul 06 19:22:05 UTC 2023 , Edited by admin on Thu Jul 06 19:22:05 UTC 2023
PRIMARY
SMS_ID
100000183596
Created by admin on Thu Jul 06 19:22:05 UTC 2023 , Edited by admin on Thu Jul 06 19:22:05 UTC 2023
PRIMARY
INN
10886
Created by admin on Thu Jul 06 19:22:05 UTC 2023 , Edited by admin on Thu Jul 06 19:22:05 UTC 2023
PRIMARY
USAN
EF-134
Created by admin on Thu Jul 06 19:22:05 UTC 2023 , Edited by admin on Thu Jul 06 19:22:05 UTC 2023
PRIMARY
NCI_THESAURUS
C170243
Created by admin on Thu Jul 06 19:22:05 UTC 2023 , Edited by admin on Thu Jul 06 19:22:05 UTC 2023
PRIMARY
FDA UNII
RZ7027HK8F
Created by admin on Thu Jul 06 19:22:05 UTC 2023 , Edited by admin on Thu Jul 06 19:22:05 UTC 2023
PRIMARY
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