POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 2

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 17:25:07 GMT 2025` Edited by `admin` on `Tue Apr 01 17:25:07 GMT 2025`
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	RY562E0KVV
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SHAW-LIKE POTASSIUM CHANNEL

Preferred Name

English

POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 2

Common Name

English

VOLTAGE-GATED POTASSIUM CHANNEL KV3.2

Common Name

English

Code System Code Type Description

UNIPROT

Q96PR1

Created by admin on Tue Apr 01 17:25:07 GMT 2025 , Edited by admin on Tue Apr 01 17:25:07 GMT 2025

PRIMARY

FDA UNII

RY562E0KVV

Created by admin on Tue Apr 01 17:25:07 GMT 2025 , Edited by admin on Tue Apr 01 17:25:07 GMT 2025

PRIMARY

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_259
N	1_266

Related Record Type Details


					46P8AHZ243

AUT-00206

POSITIVE ALLOSTERIC MODULATOR (PAM)->TARGET

Comments:

AUT00206 positively modulates recombinant human Kv3.1 and Kv3.2 mediated currents, associated with a leftward shift of channel activation. The compound has a weaker effect on Kv3.3 and Kv3.4 channels, and little or no effect on other ion channels tested.

Amount:


					BH3B64OKL9

Dalfampridine

AGONIST -> TARGET


					QZ8ETV7QYU

AUT-00201

MODULATOR->TARGET

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_600]				DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT	CHEMICAL