MESUPRINE HYDROCHLORIDE

Details

Stereochemistry	MIXED
Molecular Formula	C19H26N2O5S.ClH
Molecular Weight	430.946
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.COC1=CC=C(CCNC(C)C(O)C2=CC(NS(C)(=O)=O)=C(O)C=C2)C=C1

InChI

InChIKey=VAGQLQXTJWXCIV-UHFFFAOYSA-N

InChI=1S/C19H26N2O5S.ClH/c1-13(20-11-10-14-4-7-16(26-2)8-5-14)19(23)15-6-9-18(22)17(12-15)21-27(3,24)25;/h4-9,12-13,19-23H,10-11H2,1-3H3;1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C19H26N2O5S
Molecular Weight	394.485
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5538923 | https://www.ncbi.nlm.nih.gov/pubmed/4398626 | https://www.ncbi.nlm.nih.gov/pubmed/22185153 | https://link.springer.com/book/10.1007/978-1-4757-2085-3#about

Mesuprine is a β-adrenergic-receptor mimetic agent. It is a smooth muscle relaxant that prevents uterine contractility and premature labor.

Originator

Approval Year

PubMed

Title	Date	PubMed
Mesovarial leiomyomas in rats in a chronic toxicity study of mesuprine hydrochloride.	1972-12	4405031
The effect of mesuprine HC1 on selected smooth muscles.	1972-03	4154490
Effect of mesuprine hydrochloride upon nonpregnant uterine contractility and the cardiovascular system.	1971-09-15	4398626
Inhibition of human premature labor by mesuprine hydrochloride.	1971-01	5538923
Sulfonanilides. II. Analogs of Catecholamines.	1967-05-01	22185153

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:25:40 GMT 2025` Edited by `admin` on `Mon Mar 31 19:25:40 GMT 2025`
Record UNII	RX1N6862A8
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MJ 1987

Preferred Name

English

MESUPRINE HYDROCHLORIDE

Official Name

English

2'-HYDROXY-5'-(1-HYDROXY-2-(P-METHOXYPHENETHYL)AMINO)PROPYL)METHANESULFONANILIDE MONOHYDROCHLORIDE

Common Name

English

NSC-284706

Code

English

MJ-1987

Code

English

MESUPRINE HYDROCHLORIDE [USAN]

Common Name

English

METHANESULFONAMIDE, N-(2-HYDROXY-5-(1-HYDROXY-2-((2-(4-METHOXYPHENYL)ETHYL)AMINO)PROPYL)PHENYL)-, MONOHYDROCHLORIDE

Common Name

English

Code System Code Type Description

ChEMBL

CHEMBL2111039