MESUPRINE HYDROCHLORIDE

Details

Stereochemistry	MIXED
Molecular Formula	C19H26N2O5S.ClH
Molecular Weight	430.946
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.COC1=CC=C(CCNC(C)C(O)C2=CC=C(O)C(NS(C)(=O)=O)=C2)C=C1

InChI

InChIKey=VAGQLQXTJWXCIV-UHFFFAOYSA-N

InChI=1S/C19H26N2O5S.ClH/c1-13(20-11-10-14-4-7-16(26-2)8-5-14)19(23)15-6-9-18(22)17(12-15)21-27(3,24)25;/h4-9,12-13,19-23H,10-11H2,1-3H3;1H

HIDE SMILES / InChI

Molecular Formula	C19H26N2O5S
Molecular Weight	394.485
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5538923 | https://www.ncbi.nlm.nih.gov/pubmed/4398626 | https://www.ncbi.nlm.nih.gov/pubmed/22185153 | https://link.springer.com/book/10.1007/978-1-4757-2085-3#about

Mesuprine is a β-adrenergic-receptor mimetic agent. It is a smooth muscle relaxant that prevents uterine contractility and premature labor.

Originator

Approval Year

PubMed

Title	Date	PubMed
Inhibition of human premature labor by mesuprine hydrochloride.	1971 Jan	5538923
Effect of mesuprine hydrochloride upon nonpregnant uterine contractility and the cardiovascular system.	1971 Sep 15	4398626
Mesovarial leiomyomas in rats in a chronic toxicity study of mesuprine hydrochloride.	1972 Dec	4405031
The effect of mesuprine HC1 on selected smooth muscles.	1972 Mar	4154490

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:54:35 GMT 2023` Edited by `admin` on `Fri Dec 15 18:54:35 GMT 2023`
Record UNII	RX1N6862A8
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MESUPRINE HYDROCHLORIDE

Official Name

English

MJ 1987

Code

English

2'-HYDROXY-5'-(1-HYDROXY-2-(P-METHOXYPHENETHYL)AMINO)PROPYL)METHANESULFONANILIDE MONOHYDROCHLORIDE

Common Name

English

NSC-284706

Code

English

MJ-1987

Code

English

MESUPRINE HYDROCHLORIDE [USAN]

Common Name

English

METHANESULFONAMIDE, N-(2-HYDROXY-5-(1-HYDROXY-2-((2-(4-METHOXYPHENYL)ETHYL)AMINO)PROPYL)PHENYL)-, MONOHYDROCHLORIDE

Common Name

English

Code System Code Type Description

ChEMBL

CHEMBL2111039